摘要
目的探讨脂蛋白相关磷脂酶A2(Lp-PLA2)、同型半胱氨酸(Hcy)、高密度脂蛋白胆固醇(HDL-C)与冠状动脉病变的相关性。方法选取本院2015年1月-2016年1月收治的胸痛患者中86例作为研究对象,并根据其冠状动脉有无病变分为病变组(43例)和对照组(43例),比较2组患者血清中Lp-PLA2、Hcy、HDL-C、hs-CRP、PLT、D-二聚体水平差异。结果研究组Lp-PLA2、Hcy水平高于对照组,而HDL-C水平低于对照组,差异均有统计学意义(P<0.05)。但2组间hs-CRP、PLT、D-二聚体水平差异均无统计学意义(P>0.05)。结论 Lp-PLA2、Hcy、HDLC与冠状动脉病变密切相关,而hs-CRP、PLT、D-二聚体与冠状动脉病变无关。
Objective To investigate the relationships of serum lipoprotein- associated phospholipase A2（ Lp- PLA2）,homocysteine（ Hcy）,high density lipoprotein cholesterol（ HDL- C） with coronary artery lesion. Methods 86 patients with chest pain were collected from our hospital during Jan. 2015- Jan. 2016 and divided into the lesion group（ n = 43） and the control group（ n = 43） according to whether there was coronary artery lesion. The levels of Lp- PLA2,Hcy,HDL- C were compared between the two groups. Results The levels of Lp- PLA2 and Hcy were higher in the lesion group than those of the control group,with difference statistically significant（ P〈0. 05）. While the difference on levels of hs- CRP,PLT and D- D were not statistically significant between two groups（ P〈0. 05）. Conclusion The levels of Lp- PLA2,Hcy,HDL- C are closely associated with coronary artery lesion,while hs- CRP,PLT,D- D have nothing to do with coronary artery lesions.
作者
张卫群
王东霞
张菁菁
王伟
ZHANG Wei-qun WANG Dong-xia ZHANG Jing-jing WANG Wei(The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan 453003, Chin)
出处
《中国卫生检验杂志》
CAS
2016年第22期3269-3271,共3页
Chinese Journal of Health Laboratory Technology
