摘要
目的：研究右美托咪定对老年腹部手术患者术后镇静的临床效果及认知功能的影响。方法选择2014年1月至2015年3月行腹部手术的老年患者136例，随机将其分成对照组和治疗组，每组68例。对照组泵注氯化钠注射液，治疗组泵注右美托咪定。观察两组患者镇静效果及认知功能情况。结果治疗前，两组患者 Ram-say 评分、MMSE 评分方面比较，差异未见统计学意义（P〉0.05）；治疗后，治疗组的 Ramsay 评分与治疗前比较，差异有统计学意义（P〈0.05）；术后1、3 d，对照组的 MMSE 评分与治疗前比较，差异有统计学意义（P〈0.05）；两组患者 Ramsay 评分、MMSE 评分比较，差异有统计学意义（P〈0.05）。结论在老年腹部手术中应用右美托咪定镇静效果更明显，并且能够促进患者术后认知功能的恢复，提高患者生活质量，可推广应用。
Objective To analyze the effect of dexmedetomidine on sedation and cognitive fun-tion in elderly patient after abdominal operation. Methods One hundrad and thirty-six cases of elderly patient after abdominal operation from January 2014 to March 2015 were selected and randomly divided into control group and treatment group,with 68 cases in each group. The control group was treated by in-fusion of normal saline and the treatment group received dexmedetomidine. The sedative effect and cogni-tive function in patients of the two groups were observed. Results Ramsay score and MMSE score of the two groups of patients before the treatment were compared,and there was no significant difference（P〉0. 05）. After treatment,Ramsay scores of the treatment group were significantly different in comparison with that before treatment（P〈 0. 05）. Postoperative 1 d,3 d,the MMSE score of the control group were significantly different compared with that before treatment（P〈 0. 05）. Ramsay score and MMSE score between the two groups of patients were significantly different（P〈 0. 05）. Conclusions The sedative effect of the application of dexmedetomidine in elderly patients with abdominal surgery is more signifi-cant. It can promote the recovery of postoperative cognitive function and improve the quality of life of pa-tients,so it can be popularized and applied.
出处
《中国实用医刊》
2016年第22期94-96,共3页
Chinese Journal of Practical Medicine
关键词
右美托咪定
腹部手术
术后镇静
临床效果
认知功能
Dexmedetomidine
Abdominal surgery
Postoperative sedation
Clinical effect
Cognitive function
