摘要
[目的]观察小柴胡汤联合西药治疗肺部感染疗效。[方法]使用随机平行对照方法,将62例住院患者按病志号抽签方法简单随机分为两组;抗炎、止咳、平喘等。对照组31例头孢哌酮舒巴坦钠3.0g+生理盐水100mL,静滴,2次/d;头孢哌酮舒巴坦钠过敏改用甲磺酸左氧氟沙星300mg+生理盐水100mL,静滴,1次/d。治疗组31例小柴胡汤(黄芩、炙甘草、党参、大枣、苏子、葶苈子、柴胡、地龙各15g,半夏、杏仁各10g,炙麻黄5g;喘粗气短、动则更甚、脉象沉细加五味子10g;痰多且黄加浙贝母10g;大便秘结加大黄10g),1剂/d,水煎300mL,早晚口服;西药治疗同对照组。连续治疗10d为1疗程。观测临床症状、FEV1、PEF、症状体征改善时间、不良反应。治疗1疗程,判定疗效。[结果]治疗组完全控制16例,显效9例,有效5例,无效1例,总有效率96.77%;对照组完全控制7例,显效9例,有效9例,无效6例,总有效率80.65%;治疗组疗效优于对照组(P<0.05)。FEV1、PEF治疗组均明显改善(P<0.01),PEF对照组无明显变化(P>0.05);治疗组改善优于对照组(P<0.01)。发热消失时间、胸痛消失时间、肺部湿哆音消失时间、血常规指标检查恢复正常时间、呼吸困难消失时间治疗组均优于对照组(P<0.05),咳嗽咳痰消失时间、紫绀消失时间两组间无明显差异(P>0.05)。[结论]小柴胡汤联合西药治疗肺部感染,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Xiao Chai Hu decoction combined with western medicine in the treatment of pulmonary infection. [Method] Using random parallel control method, 62 cases of hospitalized patients according to the serial number of draw simple disease were randomly divided into two groups; anti-inflammatory, cough, and asthma. 31 cases of control group were cefoperazone sulhactam sodium 3.0g saline 100 mL, intravenous drip, 2 times/d; eefoperazone sulbactam sodium allergy modified with levofloxacin mesylate 300 mg saline 100mL, intravenous drip, 1 times/d, treatment group of 31 cases of Xiaochaihu Decoction （Radix Scutellariae, Radix Glycyrrhizae, Radix Codonopsis, jujube, perilla, Tinglizi, bupleurum root, earthworm 15g, pinellia, almond 10g, ephedra 5g; short of breath, what is more, pulse Shen plus Schisandra 10g; phlegm and yellow with the Zhejiang fritillary lOg; constipation and rhubarb 10 g）, 1 agent/d, 300 mL oral decoction, sooner or later; we sternmedicinewiththecontrolgroup. Continuous treatment with 10d for 1 courses. Observation of clinical symptoms, FEV1, PEF, improvement of symptoms and signs, adverse reactions. To determine the efficacy of 1 courses of treatment, [Results] The treatment group full control of 16 cases, 9 cases were markedly effective, 5 cases effective, 1 cases ineffective, the total efficiency of 96.77%; control group full control of 7 cases, 9 cases were markedly effective, 9 cases effective, 6 cases ineffective, the total efficiency of 80.65%; the treatment group than the control group （P〈0.05）.FEV1. PEF treatment group were improved significantly （P〈0.01）, no significant changes in the PEF control group （P〉0.05）; the treatment group was better than the control group （P〈0.01）. The disappearing time of fever, chest pain disappeared time, pulmonary rales disappeared time, blood routine examination index of recovery time, breathing difficulties disappear treatment group than in control group （P〈0.05）, cough disappeared time, cyanosis disappeared time no significant difference between the two groups （P〉0.05）. [Conclusion] Xiao Chai Hu decoction combined with western medicine in the treatment of pulmonary infection, curative effect satisfaction, no serious adverse reactions, it is worth promoting.
出处
《实用中医内科杂志》
2016年第11期53-55,共3页
Journal of Practical Traditional Chinese Internal Medicine
关键词
部感染
小柴胡汤
头孢哌酮舒巴坦钠
甲磺酸左氧氟沙星
FEV1
PEF
症状体征改善时间
中西医结合治疗
随机平行对照研究
pulmonary infection
Xiaochaihu decoction（小柴胡汤）
cefoperazone Chuba Staw Na
Levofloxacin mesylate
FEVI
PEF
symptom improvement time
treatment of traditional Chinese and Westernmedicine
randomized controlled study
