摘要
目的:探讨喉部病变对皮肌炎纵隔气肿预后的影响。方法:回顾性分析42例皮肌炎患者的临床资料,通过分析声嘶、喉部病变患者纵隔气肿的发病率及转归,评估其对皮肌炎患者纵隔气肿诊断和预后的价值。结果:42例皮肌炎患者中20例并发间质性肺炎,发病率为47.6%;4例出现声嘶,发病率为9.5%;3例并发纵隔气肿,发病率为7.1%。喉镜显示1例患者的声带表现为充血,3例声带表现为双侧声带白色改变,所有患者声带运动正常。3例声带白色改变的患者均并发纵隔气肿,并因呼吸衰竭死亡。声嘶及声带病变患者气肿的发生率及死亡率与无声带病变患者相比,差异有统计学意义(P<0.01)。结论:声嘶、喉部病变与皮肌炎患者并发纵隔气肿的产生及预后不良有一定的相关性。
Objective：To investigate the influence of laryngeal lesions on the prognosis of pneumomediastinum in patients with dermotomyositis （DM）. Method： The clinical data of patients with DM were retrospectively ana- lyzed. Hoarseness, laryngeal lesions and pneumomediastinum in patients with DM were analyzed to evaluate the influence of laryngeal lesions and hoarseness on the prognoses and diagnosis of pneumomediastinum in patients with DM. Result： Forty two patients with a diagnosis of DM were included in the study. Twenty of all the patients were diagnosed of interstitial lung disease（ILD） with the incidence of 47. 6%. Four of the patients displayed hoarseness with the incidence of 9.5 G. Three cases were complicated by pneumomediastinum with the incidence of 7.1 G. All patients have normal vocal cord movement. One of the 4 patients with hoarseness showed congestion of her vocal folds, and the other 3 patients showed white change on both of the vocal folds. All the 3 patients with white change on both vocal folds complicated by pneumomediastinum and died on respiratory failure. There were statistical differences（P〈0.01） on the prognosis and occurrence of pneumomediastinum between patients with or without hoarseness and laryngeal lesions. Conclusion： Hoarseness and laryngeal lesions may associate with poor prognosis and occurrence of pneumomediastinum in DM.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2016年第23期1870-1872,共3页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
基金
国家自然科学基金(No:81470682)
关键词
皮肌炎
气肿
声嘶
dermatomyositis
pneumomediastinum
hoarseness
