摘要
目的观察超声联合电刺激引导下A型肉毒毒素(BTX-A)注射对早期脑血管意外患者肌痉挛的影响。方法选取早期脑血管意外后小腿肌痉挛患者46例,随机分为治疗组(23例)及对照组(23例)。对照组给予常规康复训练,治疗组在常规康复训练基础上辅以超声联合电刺激引导下BTX-A注射治疗。于治疗前和治疗6周后分别采用改良Ashworth量表(MAS)、简化Fugl-Meyer量表(FMA)、世界卫生组织生存质量量表简表(WHOQOL-BREF)、表面肌电积分值(iEMG)对2组功能进行评定。结果经6周治疗后,治疗组较对照组改善,治疗组MAS、FMA、WHOQOL-BREF、iEMG评分显著高于对照组(P<0.05)。结论超声联合电刺激引导下A型肉毒毒素注射对早期脑卒中患者肌痉挛定位准确、安全有效。
Objective To observe the effect of ultrasound combined with electrical stimulation guided injection of botulinum toxin type A（BTX-A）for the treatment of spasticity in early cerebral vascular accident patients.Methods Forty-six early cerebral vascular accident patients with lower limb spasticity were divided randomly into two groups：treatment group（23patients）and control group（23 patients）.Patients in control group got routine rehabilitation training,and those in treatment group were given ultrasound combined with electrical stimulation guided injection of botulinum toxin type A additionally.The functions of two groups were evaluated by using the modified Ashworth scale（MAS）,Fugl-Meyer assessment（FMA）,intergrated electromyography（iEMG）,WHO Quality of Life-BREF（WHOQOL-BREF）before and six weeks after treatment.Results After six weeks of treatment,the treatment group improved much better than the control group.The average MAS,FMA,WHOQOL-BREF,iEMG score in treatment group were significantly higher than those of control group（P 0.05）.Conclusion Ultrasound combined with electrical stimulation guided injection of botulinum toxin type A for the treatment of spasticity in early cerebral vascular accident patients is effective,accurate and safe.
出处
《临床荟萃》
CAS
2016年第12期1340-1343,共4页
Clinical Focus
关键词
脑血管意外
A型肉毒毒素
肌痉挛
超声
电刺激
cerebral vascular accident
botulinum toxin type A
spasticity
ultrasound
electrical stimulation
