摘要
Apelin是G蛋白偶联受体APJ的特异性配体,在多种组织中均有表达。对Apelin作为一种有益的脂肪因子,可通过不同的信号通路调控糖代谢和脂代谢,并对胰岛素的分泌具有一定的调控作用,在2型糖尿病的发生和发展中起着重要的调控作用,现就Apelin对2型糖尿病的调控作用作一综述。
Apelin is ligand of APJ that is a specific G-protein-coupled receptor and universally expressed in many tissus.Apelin,as an useful adipocytokine,could regulate glucose metabolism and lipid metabolism through different signaling pathways,and possess a certain regulatory effect to the insulin secretion and play an important role in regulatory of the occurrence and development in type 2 diabetes. In the review,we described the regulatory role of apelin to type 2 diabetes.
出处
《微生物学免疫学进展》
2016年第6期93-95,共3页
Progress In Microbiology and Immunology
