摘要
目的观察冠心病(CHD)及冠心病合并抑郁症患者血清血糖和血脂水平的变化,探讨抑郁症对冠心病患者糖脂代谢相关指标的影响。方法选取2015年7月至2016年6月我院确诊的冠心病患者101例,根据抑郁量表(PHQ-9)分析,将患者分为单纯冠心病组[53例,(75.96±4.32)岁]和冠心病合并抑郁症组[48例,(74.81±5.45)岁]。比较两组患者血清葡萄糖(GLU)、果糖胺(FMN)、总胆固醇(TC)、三酰甘油(TG)、脂蛋白a(Lpa)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)以及动脉粥样硬化指数(Ai)的差异。结果单纯冠心病组中GLU、FMN、TC、TG、Lpa、HDL-C、LDL-C、Ai与冠心病合并抑郁症组比较,差异均无统计学意义(P>0.05)。结论抑郁症对冠心病患者血脂血糖无明显影响,其诱发和加重冠心病可能通过其他潜在的途径。
Objective Explore the influence of depression on glucolipid metabolism in patients with coronary heart disease（CHD）, through observe the change of serum blood glucose and lipid level. Methods Select 101 CHD patients in our hospital from July 2015 to June 2016, then divided patients into two groups by Depression Inventory： simple CHD group[53 cases, （75.96±4.32）years] and CHD with depression group[48 cases, （74.81±5.45）years]. Detection the GLU, FMN, TC, TG, Lp （a）,HDL-C, LDL-C and Ai in two groups. Results Compare with CHD complicating depression group, the level of Glu, TC, TG, HDL-CI LDL-C and Ai has no statistical difference in simple CHD group （P〉0.05）. Conclusions The depression had no significant influence on glucolipid metabolism in patients with CHD. Depression induce and aggravate CHD may through the other mechanism.
出处
《中国医药指南》
2016年第31期10-11,共2页
Guide of China Medicine
关键词
冠心病
冠心病合并抑郁症
糖脂代谢
Coronary heart disease
Coronary heart disease with depression
Glucolipid metabolism
