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血浆D-二聚体检验对急性白血病患者病情进展与效果评估分析 被引量:1

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摘要 目的:探析急性白血病患者病情进展与评价效果运用血浆 D-二聚体检验的临床效果.方法:选择2014年12月-2015年12 月期间我院收治的105例急性白血病患者作为观察组,再选择同期体检的90例健康者为对照组,运用免疫比浊法对血浆D-二聚体水平进行检测,比较分析检测结果.结果:相比较对照组而言,复发期和初治期患者的D-二聚体水平均较高,组间对比差异明显(P〈0.05);与缓解期比较,复发期、初治期患者的D-二聚体水平均较高,组间比较差异显著(P〈0.05);但是,复发期与初治期患者的D-二聚体水平比较无差异(P〉0.05);同时,不同类型白血病患者的血浆 D-二聚体水平比较差异有统计意义(P〈0.05).结论:血浆 D-二聚体检验能够将急性白血病患者的病情变化充分反映出来,并且对D-二聚体水平进行动态监测,有助于判断治疗效果. Objective: To study the clinical effect of plasma D- two test in patients with acute leukemia. Methods: 105 cases of acute leukemia patients in our hospital in December 2014 -2015 year in December as the observation group, 90 cases of healthy check-up as control group, using immune turbidimetric approach on plasma D- two level of D-dimer testing, comparative analysis of test outcomings. Results: compared with the control group, the recurrence period and initial treatment period were two D- dimer levels were higher, the difference was significant between the groups (P〈0.05); compared with remission, relapse, initial treatment in patients with stage two D- dimer levels were higher, significant difference between the two groups (P〈0.05); but there is no difference, recurrence period and initial treatment of patients with D- two level of D-Dimer (P〉0.05); at the same time, there was statistical significant difference between the plasma D- in patients with different types of leukemia and two level of D-Dimer (P〈0.05). Conclusion: plasma D- two test can fully reflect the changes of the patients with acute leukemia, and dynamic monitoring of the level of D- two polymer can help to judge the therapeutic effect.
出处 《湖南中医药大学学报》 CAS 2016年第A02期1223-1224,共2页 Journal of Hunan University of Chinese Medicine
关键词 急性白血病 D-二聚体 病情进展 acute leukemia, D- two polymer, disease progression
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