摘要
DNA中碱基的化学修饰近年来一直是生命科学领域研究的热点之一。DNA甲基化是一种常见的表观遗传现象,它能在不改变DNA序列的前提下改变遗传表型。各种胁迫因素能诱导植物DNA甲基化产生变异,但其应答胁迫机制仍然未知。本文对植物DNA甲基化研究进展进行了综述,结合本课题组的研究结果,对7Li离子束注入、^(60)CO-γ射线诱变诱导产生的DNA甲基化变异进行了报道,以期为DNA甲基化可能参与涉及植物的表型可塑性提供一定的依据。
Chemical modification of DNA bases in recent years has been one of the hot areas of life science research.DNA methylation is a common epigenetic phenomenon and can change the genetic performance without changing the DNA sequence.Various stress factors can induce the variation of DNA methylation in plants,but the response mechanism is still unknown.In this paper,the progress of DNA methylation in plants was reviewed.In combination with the research conclusions of our own research group,the DNA methylation variation induced by 7Li ion beam and gamma ray was reported to provide a basis for DNA methylation,which may be involved in the phenotypic plasticity of plants.
出处
《生物工程学报》
CAS
CSCD
北大核心
2016年第12期1642-1653,共12页
Chinese Journal of Biotechnology
基金
国家自然科学基金(No.11205055)
国家重点研发计划(No.2016YFD0102103)
"十二五"国家科技支撑计划(No.2014BAA03B04)
湖南省科技支撑计划(No.2015NK3044)资助~~
