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四物五苓汤加减治疗中心性浆液性脉络膜视网膜病变的临床研究 被引量:13

Clinical study on modified Wuling powder and Siwu decoction in central serous chorioretinopathycases
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摘要 目的观察四物五苓汤加减治疗中心性浆液性脉络膜视网膜病变的临床效果。方法研究对象选取自北京市平谷区中医院2013年1月-2015年10月期间门诊及住院收治的70例中心性浆液性脉络膜视网膜病变患者,根据治疗方案的不同分为研究组(35例)与对照组(35例)。对照组给予羟苯磺酸钙胶囊口服,研究组在口服羟苯磺酸钙胶囊的基础上给予四物五苓汤加减口服。观察两组患者临床治疗有效率、治疗前后视力水平、黄斑水肿等变化。结果两组患者治疗后临床总有效率比较,研究组(94.29%)明显优于对照组(77.14%),两组间差异有统计学意义(P〈0.05);研究组治疗后2周、6周视力水平分别为(1.32±0.27)、(1.52±0.18),对照组治疗后2周、6周视力水平分别为(0.62±0.22)、(0.89±0.25),差异有统计学意义(P〈0.05);治疗前,两组黄斑水肿高度差异无统计学意义(P〉0.05),在治疗后2周、6周研究组较对照组黄斑水肿显著降低(P〈0.05)。结论四物五苓汤加减治疗中心性浆液性脉络膜视网膜病变能够显著缩短病程,进而改善患者的视功能。 OBJECTIVE To investigate the effect of Wuling powder combined Siwu decoction in the treatment of central serous chorioretinopathy. METHODS The subjects were 70 cases with central serous chorioretinopathy patients from Pinggu Hospital dated from January 2013 to October 2015 including both outpatient and inpatient cases. Depending on the treatment program, the patients were divided into study group(35 cases) and control group(35 cases). The control group took Calcium Dobesilate Capsules orally, and study group took modified Wuling power with Siwu decoction orally in addition to Calcium Dobesilate Capsules. The clinical efficiency, visual acuity, macular edema height before and after treatment of all patients were observed. RESULTS After treatment,the total clinical effective rate of the study group(94.29%) was obviously higher than the control group(77.14%),and there was a significant difference between the two groups(P〈0.05); two weeks and 6 weeks after treatment, visual acuity level of study group were 1.32 ±0.27 and 1.52 ±0.18, while results of control group were 0.62 ±0.22 and 0.89±0.25, which indicated that the difference was significant(P〈0.05). Before treatment,there was nohighly significant difference between the two groups in terms of macular edema(P〈0.05), however, 2 weeks and 6 weeks after treatment, the study group enjoyed a significantly reduce of macular edema than the control group(P〈0.05).CONCLUSIONS Wuling powder combined Siwu decoction received better clinical efficacy on central serous chorioretinopathy, in that it could significantly shorten the course, and improve the patient's visual function.
作者 景大瑞 韦企平 JING Darui WEI Qiping(Beijing Pinggu Hospital of Traditional Chinese Medicine, Beijing 101200, China)
出处 《中国中医眼科杂志》 2016年第5期306-309,共4页 China Journal of Chinese Ophthalmology
关键词 五苓散 四物汤 中心性浆液性脉络膜视网膜病变 黄斑水肿 新生血管 Wuling powder Siwu decoction central serous chorioretinopathy macular edema angiogenesis
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