摘要
目的分析CT血管造影(CTA)对脑梗死伴颈动脉狭窄患者脑血流动力学改变的评价作用。方法收集2012年3月-2015年10月我院收治的50例脑梗死伴颈动脉狭窄患者的临床资料,所有患者均经经颅多普勒超声(TCD)提示存在不同程度狭窄或闭塞表现,入院后均完成CTA、CT灌注扫描(CTP)检查,分析CTA对患者脑血流动力学改变的评估价值。结果对照组、轻度狭窄、中度狭窄患者额叶、颞叶、基底节区脑血流动力学参数对比差异无统计学意义(P>0.05);重度狭窄、完全闭塞组患者额叶、颞叶、基底节区CBF低于对照组,CBV、MTT、TTP均高于对照组(P<0.05);CTA检出正常43支,轻度狭窄9支,中度狭窄12支,重度狭窄23支,闭塞13支,与TCD结果一致性较高(P<0.05)。结论 CTA配合CTP检查有助于综合评估脑梗死伴颈动脉狭窄患者脑血流动力学改变情况,可为临床治疗提供影像学指导。
Objective To analyze the effect of CT angiography（CTA） in evaluation of cerebral hemodynamic changes in patients with cerebral infarction complicated with carotid stenosis. Methods The clinical data of 50 patients with cerebral infarction and carotid stenosis admitted in our hospital between March 2012 and October 2015 were collected. All patients were examined by transcranial Doppler ultrasound（TCD）, indicating there were different degrees of stenosis or occlusion. CTA and CT perfusion scan（CTP） were performed after admission. The value of CTA in evaluating the cerebral hemodynamic changes in patients was analyzed. Results There were no significant differences in the hemodynamic parameters of frontal lobe, temporal lobe and basal ganglia between patients in control group, patients with mild stenosis and patients with moderate stenosis（P〉0.05）. CBF of frontal lobe, temporal lobe and basal ganglia in patients with severe stenosis or total occlusion were lower than those in control group while CBV, MTT and, TTP and CBF were higher than those in control group（P〈0.05）; CTA showed 43 normal branches, 9 branches with mild stenosis, 12 branches with moderate stenosis, 23 branches with severe stenosis, and 13 branches with occlusion. The consistency with the results of TCD was high（P〈0.05）. Conclusion CTA combined with CTP examination is helpful to the comprehensive evaluation of cerebral hemodynamic changes in patients with cerebral infarction complicated with carotid stenosis, which can provide imaging guidance for clinical treatment.
出处
《中国CT和MRI杂志》
2017年第1期26-29,共4页
Chinese Journal of CT and MRI
关键词
脑梗死
颈动脉狭窄
CTA
脑血流动力学
Cerebral Infarction
Carotid Stenosis
CTA
Cerebral Hemodynamics
