摘要
目的探讨2型糖尿病患者波动性高血糖与糖尿病肾病的关系。方法选取2012年1月至2015年1月2型糖尿病患者100例,检测糖化血红蛋白(Hb A1c),并根据检测结果对患者进行分组,其中Hb A1c<9.0%者44例,Hb A1c≥9.0%者56例。根据患者的血糖变异系数(CV)再次对患者进行分组,包括血糖平稳组及血糖波动组,划分标准参照CV=0.29。测定空腹血糖值、Hb A1c、血脂各指标,观察各组糖尿病肾病的发生率,了解波动性高血糖与糖尿病肾病的关系。结果 CV值≥0.29组糖尿病肾病发病率均高于CV值<0.29组。四组以Hb A1c≥9.0%组糖尿病肾病发病率最高。结论 2型糖尿病患者中,波动性高血糖患者易诱发糖尿病肾病,需引起临床的高度重视,积极做好预防工作,降低并发症的发生,维护患者的健康。
Objective To investigate the relationship between volatility hyperglycemia and diabetic nephropathy in type 2 dia-betes mellitus patients. Methods One hundred patients from January 2012 to January 2015 with type 2 diabetes were chosed, and patients were grouped according to the test results,in which glycated hemoglobin（ HbA1c）〈 9. 0% in 44 cases and HbA1c≥9. 0% in 56 cases. Patients were grouped again according to their blood glucose coefficient of variation（CV）：blood glucose stable group and blood glucose fluctuation group,division standard reference CV = 0. 29. The fasting blood glucose level （FBG）,HbA1c and blood lipids indexes were measured,the incidence rate of diabetic nephropathy was observed in each group, in order to understand the relationship between volatility hypertension and diabetic nephropathy. Results The result showed,the incidence rates of diabetic nephropathy in patients with CV values ≥0. 29 was higher than that in patients with CV values 〈0. 29. The incidence of diabetic nephropathy in HbA1c≥9. 0% group was the highest among the four groups. Conclusion Pa-tients with volatility hyperglycemia is easily induced diabetic nephropathy in type 2 diabetes mellitus patients,which needs more attention and do a good job for active prevention,reduce the complications and maintain the patient’s health.
出处
《临床医学》
CAS
2016年第12期13-15,共3页
Clinical Medicine
关键词
2型糖尿病
波动性
高血糖
糖尿病肾病
关系
Type 2 diabetes
Volatility
Hyperglycemia
Diabetic nephropathy
Relations
