摘要
目的了解我院创建癌痛规范化治疗示范病房（GPM）前后麻醉性镇痛药的使用情况，以进一步指导临床癌痛规范化治疗。方法采用药物用药频度（DDDs）分析法、金额排序法、日均费用（DDC）及药品排序比（B／A）对比分析我院2014—2015年麻醉性镇痛药的用药情况。结果我院创建GPM以来，麻醉性镇痛药DDDs总量呈上升趋势，使用增加到16个品规，DDDs排名前三的仍是羟考酮缓释片、芬太尼透皮贴剂和吗啡缓释片，金额排名前三的是羟考酮缓释片、吗啡缓释片和关沙酮片。金额排序与DDDs排序同步性较好，说明药物费用较合理。大部分麻醉性镇痛药的DDC基本稳定，其B／A值接近1。结论我院麻醉性镇痛药的合理使用在创建GPM以来卓有成效。但仍存在整体麻醉性镇痛药DDDs偏小等不足。
Objective To investigate the usage of narcotic analgesics in our hospital before and after the implementation of GPM and to standardize the clinical treatment of cancer pain. Methods The data of narcotic analgesics use during 2014 and 2015 were analyzed with the methods of DDDs, DDC, ranking of consumption sum and sequential ratio （B/A）. Results The total DDDs of narcotic analgesics had increased, and up to 15 kinds of narcotic analgesics have been used since practicing GPM. The top three DDDs of narcotic analgesics were still oxycodone sustained-release tablets, transdermal fentanyl and morphine sustained-release tablets. In terms of consumption sum, the top three were oxycodone sustained-release tablets, morphine sustained-release tablets and methadone tablets. The good synchronization between consumption sum ranking and DDDs indicated that the drug cost was reasonable. Most of narcotic analgesics had their DDC being stable and their B/A close to 1. Conclusion The narcotic analgesics use in our hospital had been effective since practicing GPM. But there were still deficiencies such as small overall narcotic analgesics DDDs. It was still necessary to promote the WHO Three Ladder Analgesic Principle for Cancer Pain actively, and achieve a reasonable and standardized treatment of cancer pain.
作者
蔡莉莉
周虹
林志强
洪珊珊
张清泉
CAI Lili ZHOU Hong LIN Zhiqiang HONC Shanshan ZHANG Qingqnan(Department of Pharmacy, Quanzhou Municipal First Hospital, Quanzhou, Fujian, 362000, Chin)
出处
《肿瘤药学》
CAS
2016年第6期471-476,共6页
Anti-Tumor Pharmacy
基金
2014年福建省卫生计生委青年科研课题(2014-2-50)
