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CRRT在脓毒血症急性肾损伤患者救治中的临床研究 被引量:14

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摘要 目的:探讨连续肾脏替代疗法(CRRT)在脓毒血症急性肾损伤患者救治中的临床疗效。方法:选取2014年1月-2016年1月于笔者所在医院就诊的脓毒血症急性肾损伤患者86例,按入院编号随机分为观察组与对照组,各43例,对照组给予常规药物治疗,观察组行CRRT治疗,比对疗效。结果:治疗后两组舒张压(DBP)、收缩压(SBP)及平均动脉压(MAP)均较治疗前好转,治疗后观察组DBP、SBP、MAP及血氧饱和度(Sp O2)均优于对照组,但差异无统计学意义(P>0.05);治疗后两组患者尿量均明显增多,观察组患者尿量增多程度高于对照组,差异有统计学意义(P<0.05);治疗后观察组与对照组相比,除血红蛋白(Hb)差异无统计学意义(P>0.05)外,白细胞计数(WBC)、血小板计数(PLT)、超敏C反应蛋白(hs-CRP)、血清肌酐(Scr)、中性粒细胞(N)、尿素氮(BUN)差异均有统计学意义(P<0.05);治疗后观察组肾功能恢复比例及死亡率均明显优于对照组,差异有统计学意义(P<0.05)。结论:脓毒血症急性肾损伤患者救治时采用CRRT可有效改善患者机体内环境,清除体内潴留代谢废物及炎症因子,控制血流动力学指标,提升存活率,疗效确切,值得推广。
作者 邓云
出处 《中外医学研究》 2016年第35期46-48,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
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