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4例非妊娠性绒毛膜癌临床病理分析 被引量:6

Clinicopathological analysis of nongestational choriocarcinoma in 4 cases
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摘要 目的探讨非妊娠性绒毛膜癌的临床表现、病理特征、治疗和预后情况。方法回顾性分析该院4例非妊娠性绒毛膜癌患者的临床及病理资料,并复习相关文献。结果 4例患者初诊均未得到明确诊断,所有患者均接受手术治疗及术后行BEP方案化疗;随访3~32个月。1例术后26个月时因肺转移死亡;1例失访;2例一般情况可。结论非妊娠性绒毛膜癌是罕见的高度侵袭性的滋养叶细胞肿瘤,易早期发生血行转移,治疗推荐采用手术及术后结合多药联合化疗。 Objective To investigate the clinical manifestations,pathological features,treatment and prognosis of nongesta- tional choriocarcinomas. Methods The clinicopathological data in 4 cases of nongestational chorioeareinoma were retrospectively analyzed and the relevant literatures were reviewed. Results All 4 patients had no confirmed diagnosis at first visit to hospital. All patients received the operative therapy and postoperative bleomycin,etoposide and cis-platinum (BEP) regimen chemotherapy. The followed up lasted for 3-32 months. One ease died at postoperative 26 months due to pulmonary metastasis;one ease was loss of follow up;two cases had relatively favorable condition. Conclusion Nongestational ehorioeareinoma is a rare and highly invasive trophoblastie neoplasm,and is prone for early distant metastasis. The treatment is recommended to adopt operation combined with postoperative combined chemotherapy of multiple drugs.
出处 《重庆医学》 CAS 北大核心 2017年第1期75-77,共3页 Chongqing medicine
关键词 绒毛膜癌 睾丸 隐睾 卵巢 非妊娠性 chorioearcinoma testis cryptorchidism ovary nongestational
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