摘要
目的评价"川椒方"治疗过敏性结膜炎的有效性。方法采用双盲、双模拟、阳性药西替利嗪对照,将符合纳入标准的122例过敏性结膜炎患者随机分为治疗组和对照组。其中治疗组口服川椒方颗粒剂及西替利嗪安慰剂,对照组口服西替利嗪胶囊及川椒方颗粒剂安慰剂。分别于治疗前、治疗1周后、治疗2周后,评价两组患者的眼部症状、体征。结果两组治疗后与治疗前症状体征积分比较:治疗2周后<治疗1周后<治疗前,经分析,差异具有统计学意义(P<0.05)。两组间眼部症状、体征积分比较:治疗1周后,治疗组<对照组,差异无统计学意义(P>0.05);治疗2周后,治疗组<对照组,差异具有统计学意义(P<0.05)。结论川椒方治疗过敏性结膜炎有效,且优于西替利嗪。
Objective To eyaluate the therapeutic efficacy of ＂ Chuanjiao Decoction＂ for treatment of patients the allergic con- junctivitis. Methods This research was adopted the double blind and double simulation, positive medicine Cetirizine comparison, including 122 patients with allergic conjunctivitis which were randomly divided into treatment group and control group. The treat- ment group was given ＂ Chuanjiao Decoction＂ and Cetirizine placebo, while the control group was given Cetirizine capsule and ＂ Chuanjiao Decoction＂ placebo. Respectively we evaluated ocular symptoms and signs of two groups on the time points before treat- ment, 1 weeks after treatment and 2 weeks after treatment. Results The score comparison of symptoms and signs between the two groups 2 weeks after treatment, 1 week after treatment and before treatment： the score of 2 weeks after treatment is lower than that of 1 week after treatment , which lower than that of before treatment , which the difference was statistically significant （ P 〈 0.05 ）. The score comparison of symptoms and signs between the two groups ： 1 week after treatment, the score of the treatment group is lower than that of the control group, but there was no statistically significant difference （P 〉 0.05） ;2 weeks after treatment, thescore of the treatment group is lower than that of the control group, difference has statistical significance （P 〈 0.05 ）. Conclusion It is effective for Chuanjiao Decoction treating allergic conjunctivitis , and the efficacy of Chuanjiao Decoction is better than that of Cetirizine.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2016年第12期2936-2939,共4页
Lishizhen Medicine and Materia Medica Research
基金
中国中医科学院科研项目(No.ZZ070871)
中国中医科学院"名医名家传承"项目(No.CM2014GD1032)
关键词
川椒方
过敏性结膜炎
西替利嗪
双盲
Chuanjiao Decoction
Allergic conjunctivitis
Cetirizine placebo
Double - blind
