摘要
目的研究富血小板血浆(Platelet-rich plasma,PRP)对股骨颈骨折患者骨折愈合以及股骨头坏死治疗效果的影响。方法选择股骨颈骨折患者100例,按照简单数字表法随机分为试验组和对照组各50例。对照组采用空心钉内固定手术;试验组在对照组治疗的基础上术后采用富血小板血浆(PRP)治疗。定期随访术后12个月内两组情况,观察记录两组患者性别、骨折部位、骨折类型。结果对照组与试验组患者术后股骨头坏死率分别为12例(27.9%)和3例(6.9%),对照组患者股骨头坏死率明显高于试验组,试验组患者的愈合率为40例(93.0%),明显提高了患者的骨折愈合率和降低了股骨头坏死率。两组患者术后Harris评分、多时间点、组间比较差异明显(F=11.13,P=0.003、F=4.25,P=0.032、F=5.34,P=0.022),12个月内对照组患者的Harris评分为(85.25±11.52),试验组患者的Harris评分为(92.15±12.85),试验组明显高于对照组,差异具有统计学意义(P<0.05)。结论富血小板血浆能有效促进股骨颈骨折患者术后恢复,且能缩短恢复时间。
Objective To study the effect of platelet rich plasma on fracture healing and femoral head necrosis in patients with femoral neck fracture. Methods 100 patients with femoral neck fracture were randomly divided into experimental group and control group. The control group was treated with cannulated screw fixation. The experimental group was treated with postoperative platelet rich plasma （PRP） treatment based on control group. The patients were followed up for two months after operation. Results The femoral head necrosis rates of experimental group （6.9%） was lower than that of control group （27.9%） （P〈0.05）. The healing rate of experimental group were 93.0%. Harris hip score of experimental group and control group were 85.25± 11.52 and 92.15± 12.85 （P〈0.05）. Conclusion Platelet rich plasma can effectively promote the recovery of patients with femoral neck fracture and shorten the recovery time.
出处
《西部医学》
2017年第1期103-105,109,共4页
Medical Journal of West China
基金
四川省科技厅资助项目(2014SZ0035)
