摘要
目的:了解大型眼科诊疗中心的用药构成,指导和加强眼科用药的药事管理。方法:调取某大型眼科诊疗中心2013-2015年眼科用药的销售金额和销售数量等数据,采用销售金额、限定日剂量和用药频度分析的方法,进行数据处理、分析及评价。结果:该中心眼科用药共涉及五大类26亚类135个品规,眼科其他用药占眼科用药总销售金额的56.70%,占总销售数量的52.42%;人工泪液、眼润滑剂和收敛药的销售金额及销售数量均排名第1;抗细菌药物是最常用的眼部感染用药;眼用抗炎药以其他抗炎药为主,糖皮质激素为辅;青光眼用药中的前列腺素类似物和碳酸酐酶抑制剂等的序号比(B/A)<0.5。国产眼科药品占药品总销售金额的57.77%,占总销售数量的69.42%。眼科用药的基本药物仅占总销售金额的7.92%。局部外用抗菌药物使用率门诊>30.00%,住院>94.00%。激素冲击疗法不良反应发生率为17.19%。结论:辅助用药应成为眼科用药药事管理的重点;应加强眼用抗细菌药、前列腺素类似物、糖皮质激素的专科用药管理,促进其合理使用;国产药品占据眼科用药主流,但研发有待加强;眼科基本药物供应短缺,亟待充实基本药物目录。
OBJECTIVE ： To investigate the constitution of drug use in large-scale ophthalmic center, and to guide and strengthen pharmaceutical administration of ophthalmic medication. METHODS： The data of consumption sum and quantity of ophthalmic drugs was obtained from a large-scale ophthalmic center during 2013-2015, which was processed, analyzed and evaluated with a method of consumption sum, DDD and DDDs analysis. RESULTS： 5 categories were involved, including 26 subcategories, 135 speification. The consumption sum of other ophthalmic drugs accounted for 56.70% of total consumption sum, and the proportion of consumption quantity was 52.42%. Artifical tears, ophthalmic lubricant and astringent took up the first place of consunption sum and quatitity. Antibiotics were the most commonly used ophthalmic drugs for infection. The ophthalmic anti-inflammatory drugs were mainly other kinds of anti-inflammatory drugs, supplemented by glucocorticoid. Serial number ratio （B/A） of prosta- glandin analogue and carbonic anhydrase inhibitor, etc among drugs for glaucoma was lower than 0.5. The domestic ophthalmic drug accounted for 57.77% of total consumption sum and 69.42% of total consumption quantity. The ophthalmic essential medicine only shared 7.92% of total consumption sum. The proportion of antibiotics for local external use was higher than 30.00% in outpa- tient department and higher than 94.00% in the inpatient department. The incidence of ADR induced by high-dose corticosteroid therapy was 17.19 %. CONCLUSIONS： Assistant medication ought to become a key point of ophthalmic pharmaceutical administration. It is necessary to strengthen specialty medication management of ophthalmic antibiotics, prostaglandin analogue and glucocorticoid so as to promote rational use of them. Domestic drugs share the main ophthalmic medication market, but domestic drugs R＆D is to be strengthened. Ophthalmic essential medicine is in short supply, and it is urgent to enrich essential medicine list.
出处
《中国药房》
CAS
北大核心
2017年第2期164-170,共7页
China Pharmacy
关键词
眼科用药
药物利用分析
药事管理
合理用药
Ophthalmic medication
Analysis of drug utilization
Pharmaceutical administration
Rational drug use
