摘要
目的探讨影响脑出血并发急性上消化道出血(acute upper gastrointestinal bleeding,AUGIB)的危险因素,为脑出血并发AUGIB的防治提供理论依据。方法回顾性分析2013年5月-2015年7月孝感市中心医院神经内科收治的291例脑出血患者,根据发病后14 d内有无并发AUGIB分为出血组和无出血组,采用随访观察和Logistic回归分析等方法,探讨脑出血并发AUGIB的危险因素。结果脑出血并发AUGIB的发病率为24.40%,其中以脑出血量≥30 ml发生率(77.46%)最高。单因素和多因素分析均显示血压≥180/100 mm Hg、脑出血量≥30 ml、GCS评分低、颅内压增高、败血症、脑出血部位与脑出血并发AUGIB关系密切(P<0.05),是其发病的独立危险因素。结论脑出血并发AUGIB是多因素共同作用的结果,特别是基底节区出血,临床上应积极治疗原发病、保护胃肠功能,以降低脑出血并发AUGIB的发生率。
Objective To explore the risk factors of cerebral hemorrhage compliated with acute upper gastrointestinal bleeding （AUGIB） , and provide theoretical basis for clinical prevention and treatment. Methods Two hundred and ninety-one cases of cerebral hemorrhage patients in Xiaogan Central Hospital from May. 2013 to Jul. 2015 were analyzed retrospectively. According to whether there had AUGIB within 14 days of onset, they were divided into hemorrhage group and non-hemorrhage group. The risk factors of cerebral hemorrhage complicated with AUGIB were discussed by means of follow-up observation and Logistic regression. Results The incidence of cerebral hemorrhage complicated with AUGIB was 24.40% , and incidence of the volume of cerebral hemorrhage ≥30 ml was the highest, which accounted for 77.46%. Both the univariate and multivariate analysis showed that blood pressure ≥ 180/100 mmHg, the volume of cerebral hemorrhage 330 ml, lower GCS score, increased intracranial pressure, sepsis and cerebral hemorrhage sites were independent risk factors and closely related with cerebral hemorrhage complicated with AUGIB （ P 〈 0.05 ）. Con- clusion The incidence of cerebral hemorrhage complicated with AUGIB is high, it is the result of interactions of multi- ple factors in special for basal ganglia hemorrhage. Therefore, in clinic, active treatment of primary disease and early protection of gastrointestinal function are essential in order to reduce the incidence of cerebral hemorrhage complicated with AUGIB.
出处
《胃肠病学和肝病学杂志》
CAS
2016年第12期1451-1454,共4页
Chinese Journal of Gastroenterology and Hepatology
