摘要
目的:观察尿毒症维持性血透患者骨密度降低发病情况、分析其影响因素。方法:选择2015年8月在我院维持性血透3月以上的99例尿毒症血透患者,使用双能X线测定腰椎、股骨颈骨密度,收集一般资料和生化指标。单因素分析骨密度的相关因素,多因素非条件logistic回归骨密度降低危险因素。结果:骨密度异常率73.73%,其中腰椎64.64%,股骨颈59例59.59%。非条件logistic回归分析结果:OSTA(腰椎:OR=0.775,P=0.01;股骨颈:OR=0.753,P=0.001);铁蛋白(腰椎:OR=1.003,P=0.07;股骨颈:OR=1.002,P=0.048);男性(股骨颈:OR=0.356,P=0.039)。结论:持续性血液透析(Maintenance hemodialysis,MHD)患者骨矿物质密度(Bone mineral density,BMD)降低常见,亚洲人的骨质疏松自我评估工具(Osteoporosis Self-assessment Tool for Asians,OSTA)、铁蛋白、性别是MHD患者骨密度异常的危险因素。
Objective：To learn about the incidence and risk factors of the abnormal bone mineral density（BMD）in maintenance hemodialysis（MHD）patients.Methods：Ninety-nine MHD patients in our hemodialysis center in August 2015 were enrolled and received MHD treatment over 3months.Lumbar and femoral neck BMD value were measured by X-ray absorptiometry and the age,gender,height,weight,dialysis vintage of patients were observed.The BMD data was analyzed by one-way ANOVA and logistic regression analysis was performed to identify the risk factors of the abnormal BMD.Results：The rates of abnormal BMD,lumbar femoral neck were 3.73%,64.64%,59.59%,respectively.The results of unconditional logistic regression showed that OSTA（lumbar：OR=0.775,P=0.01;femoral neck：OR=0.753,P=0.001）,ferritin（lumbar：OR=1.003,P=0.07;femoral neck：OR=1.002,P=0.048）.Male（femoral neck：OR=0.356,P=0.039）.Conclusion：The prevalence of abnormal BMD was higher in MHD patients;OSTA,ferritin,gender were the risk factors for abnormal BMD.
出处
《四川生理科学杂志》
2016年第4期199-202,共4页
Sichuan Journal of Physiological Sciences
基金
攀枝花市科技局资助项目(编号:2015CY-5-32)
关键词
维持性血液透析
骨密度异常
铁蛋白
Maintenance hemodialysis
Bone mineral density abnormality
Ferritin
