摘要
目的对比不同剂量奥美拉唑对非静脉曲张上消化道的疗效。方法 2014年2月—2016年3月,对142例患者采用随机数字表法分组,小剂量组、大剂量组各入组71例,在禁水食、输血等常规治疗基础上,分别给予40、80 mg奥美拉唑,泵入,对比临床疗效、禁食时间等指标。结果大剂量组控制+显效率98.6%高于小剂量组78.9%,大剂量组禁食时间(2.1±1.6)d低于小剂量组(3.6±1.4)d,72 h后两组组内比较HB、HCT高于治疗前,组间对比,大剂量组分别为(86.3±10.2)g/L、(35.5±5.3)%高于小剂量组(80.4±11.3)g/L、(32.3±5.4)%,差异有统计学意义(P<0.05)。结论大剂量治疗奥美拉唑治疗非静脉曲张上消化道疗效肯定,可增进疗效。
Objective To compare the efficacy of different doses of omeprazole for non variceal upper gastrointestinal tract.Methods From February 2014 to March 2016,In 142 cases were treated by random number expression grouping,low dose group,high dose group,the group of 71 cases,on the basis of conventional treatment,such as water deprivation,blood transfusion.,were treated with 40 mg,80mg omeprazole,pump,compare the clinical curative effect,fasting time and other indicators.Results The large dose group ＋ control rate was 98.6% higher than 78.9% in the low dose group,high dose group fasting time（2.1±1.6）d lower than the low dose group（3.6±1.4）d,HB in the two groups after 72 h,HCT was higher than that before treatment,the comparison between the two groups,high dose group（86.3±10.2）g/L,（35.5±5.3）% higher than that of low dose group（80.4±11.3）g/L,（32.3±5.4）%,the difference was statistically significant（P 〈 0.05）.Conclusion High dose omeprazole treatment Non varicose upper gastrointestinal effect is certain,can enhance the efficacy.
出处
《世界复合医学》
2016年第4期63-65,共3页
World Journal of Complex Medicine
