摘要
①目的探讨成人住院2型糖尿病患者发生低血糖的相关影响因素。②方法选择我院内分泌科2016年3~8月收治的成人2型糖尿病患者525例,其中住院期间发生低血糖者为观察组,共73例;同期住院未发生低血糖者为对照组,共452例。通过回顾性对比研究患者一般临床资料与生化指标,分析成人住院2型糖尿病患者发生低血糖的相关影响因素。③结果 525例成人住院2型糖尿病患者中发生低血糖者73例,低血糖发生率为13.9%。其中午餐前低血糖发生率最高,其次为睡前及晚餐前。两组患者在年龄、体质量指数(BMI)、糖化血红蛋白、治疗方案方面差异有统计学意义(P<0.05)。经Logistic回归分析,年龄(OR=1.034,P=0.025)、BMI(OR=0.823,P=0.000)、糖化血红蛋白(OR=0.812,P=0.038)及治疗方案(P=0.001)是低血糖的影响因素。年龄是成人住院2型糖尿病患者发生低血糖的危险性因素,与低血糖的发生呈正相关,而BMI、糖化血红蛋白是发生低血糖的保护性因素,与低血糖的发生呈负相关。④结论年龄是成人住院2型糖尿病患者发生低血糖的危险性因素,而BMI、糖化血红蛋白是发生低血糖的保护性因素。故在临床工作中,应加强对低血糖发生高危时段的血糖监测;对BMI较低、糖化血红蛋白接近正常水平的高龄住院2型糖尿病患者需及时调整治疗方案,避免低血糖的发生。
Objective To explore the factors which affect the hypoglycemia in adult hospitalized patients with type 2 diabetes. Methods A total of 525 patients with type 2 diabetes in adults were chosed from March to August 2016 in our hospital,included hypoglycemia occurred during hospitali- zation for observation group（n=73）,without the hypoglycemia as control group（n =452）.Through a retrospective comparative study in patients with general clinical data and biochemical indicators,ana- lyzed the hypoglycemia hospitalized adult patients with type 2 diabetes related influencing factors. Re- sults A total of 525 adult hospitalized patients with type 2 diabetes,73 cases developed hypoglycemi- a,the incidence of hypoglycemia was 13.9%.The highest incidence of hypoglycemia was before lunch followed by going to bed and before dinner.Two groups had significant difference in age,BMI, HbAlc and therapeutic regimen. Logistic regression analysis, age （OR = 1.034, P = 0.025）, BMI （OR = 0.823, P = 0.000）, HbAlc（OR= 0.812, P = 0.038） and therapeutic regimen（P = 0.001） were influence factors of hypoglycemia.Age was hospitalized adult patients with type 2 diabetes risk factor of hypoglycemia, positively correlated with the incidence of hypoglycemia, and BMI, HbAlc were protective factors, and negatively correlated with the occurrence of hypoglycemia. Conclusion Age is hospitalized adultpatients with type 2 diabetes risk factor of hypoglycemia, and BMI, HbAlc are protective factors. Therefore, in clinical work, high risk for hypoglycemia happened time blood glucose monitoring should be strengthened and the lower BMI, HbAlc, close to normal venerable age adults hospitalized patients with type 2 diabetes need to adjust the treatment plan in time,avoid the happening of hypo- glycemia.
作者
王晓迪
金秀平
刘长丽
WANG Xiaodi JIN Xiuping LIU Changli(North China University of Science and Technology, Tangshan 063000, Chin)
出处
《华北理工大学学报（医学版）》
2017年第1期28-31,共4页
Journal of North China University of Science and Technology：Health Sciences Edition
关键词
成人2型糖尿病
低血糖
影响因素
Adults with type 2 diabetes.Hypoglycemia.Influence factors
