摘要
黄连是毛茛科、黄连属多年生草本植物的干燥根茎,具有清热燥湿、泻火解毒之功,现代研究发现黄连有广谱抗菌、抗心律失常、降血压、调节脂代谢等作用,近年来临床和实验研究表明黄连具有显著抗肿瘤作用,该文详细阐述了黄连抗肿瘤的临床外用、内服研究进展以及黄连临床运用安全性评估的进展,并且总结提出了黄连目前临床研究的不足,为黄连未来研究提供新的思考。
Rhizoma Coptidis is one of the herbaceous perennid rhizome belongs to buttercup family and the effects of it are clearing away heat and purging fire for removing toxin. Modern medical research has proved that its extract plays an important role in antibacterial,anti-arrhythmic,adjust blood pressure and resistance to high cholesterol. In recent years,study found Rhizoma Coptidis restraining tumor cell proliferation,inducing tumor cell apoptosis and it has been widely used in the treatment of tumors. This paper expounds the external,internal clinical application and safety evaluation of the effect on Rhizoma Coptidis antitumor. We have some summarizes and analyzes on the deficiencies of the clinical research and some expectations are proposed at last.
出处
《辽宁中医药大学学报》
CAS
2017年第1期131-133,共3页
Journal of Liaoning University of Traditional Chinese Medicine
基金
国家自然科学基金青年科学基金项目(81403262)
关键词
黄连
临床研究
肿瘤
安全性
Rhizoma Coptidis
clinical research
tumor
safety assessment
