摘要
目的 探讨减少1 8F 脱氧葡萄糖 (FDG)PET显像胃肠道生理性浓聚的方法及其临床价值。方法 常规1 8F FDGPET全身或腹部显像者 5 0例。减少胃肠道生理性浓聚的方法包括 :普鲁苯辛预处理者 12例 ,灌肠 +普鲁苯辛预处理 3例 ,延迟再显像 7例 ,进食后再显像 4例 ,隔天再显像 2例。结果 5 0例常规显像者中 4 4 % (2 2例 )胃肠道浓聚影高于肝影 ;12例普鲁苯辛预处理者 ,胃肠影高于肝影者仅 1例 (8% ) ,与常规显像组比较差异有显著性 (P <0 .0 5 ) ;3例灌肠 +普鲁苯辛预处理者肠道未见浓聚影 ;2例进食后再显像、3例延迟再显像及 2例隔天再显像者 ,首次显像出现胃或肠道浓聚 ,再次显像浓聚影形态明显改变或消失 ,明确为生理性浓聚 ;4例大肠癌患者延迟显像病灶形态及位置未见明显改变 ;另 2例恶性肿瘤患者进食后再显像 ,病灶与胃的关系更清晰。结论 胃肠道生理性浓聚是一种常见现象 ,灌肠和 (或 )普鲁苯辛预处理可降低其发生率 ;延迟显像、进食后再次显像、隔天再显像有助于明确是否为胃肠道生理性浓聚 。
Objective To investigate the clinical practicability of several methods for eliminating the physiological FDG accumulation in the stomach and intestine in PET imaging and to improve the diagnostic accuracy. Methods Whole body FDG PET scan was performed on 50 study subjects as routine imaging at 45～60 min after FDG injection. Some methods for eliminating the stomach and intestinal FDG accumulation. In addition to the routine imaging group, there were 12 cases pretreated with oral probanthine,3 cases with enema and probanthine pretreatment, 7 cases with delayed rescanning, 4 cases with postprandial rescanning and 2 cases rescanning the next day. Results The stomach and intestinal FDG accumulation was observed at a rate of 44%(22/50) in routine imaging group and was obviously higher than 8%(1/12) of probanthine pretreatment group ( P <0.05 among two groups). No obviously high stomach and intestinal FDG uptake was found in PET images with enema and probanthine pretreatment. The intensity, shape and position of intestinal high FDG accumulation changed obviously and so was defined as intestinal physiological uptake in 2 cases with delayed reimaging, 3 cases with postprandial reimaging and 2 cases with reimaging the next day, but the hot foci of colorectal lesions did not changed between routine images and delayed images in 4 patients with colorectal cancer .In another two patients, the locations of the lesions against the stomach displayed more clearly in postprandial images. Conclusions The intestinal physiological accumulation of FDG is a common phenomenon. Enema and probanthine pretreatment could reduce its occurrence. Several reimaging methods may help to define whether it is stomach and/or intestinal physiological high uptake or lesions. These methods are of clinical practicability.
出处
《中华核医学杂志》
CAS
CSCD
北大核心
2002年第4期235-236,共2页
Chinese Journal of Nuclear Medicine
