摘要
目的：探讨颅内破裂动脉瘤术前再出血的相关危险因素，为早期预防再出血提供依据。方法采用回顾性病例对照的方法，对465例确诊的颅内破裂动脉瘤患者进行回顾性调查；依据入院后2周内是否发生再出血分为再出血组（n=113）和未再出血组（n=352），采用单因素和多因素的方法来筛选影响再出血的相关危险因素。结果颅内破裂动脉瘤术前再出血发生率高达24.3%（113/465）；多因素分析结果显示高血压病史（OR=4.092），合并脑血管痉挛（OR=1.893），癫痫（OR=3.013），肿瘤直径（OR=2.787），过早搬动或下床活动（OR=4.179）等均为颅内破裂动脉瘤患者术前再出血的危险因素。结论颅内破裂动脉瘤患者术前仍然有较高的再出血发生率，严重影响患者的预后；影响术前再出血的危险因素较多，应针对这些独立高危因素采取必要干预措施。
Objective To explore the correlated risk factors of rehaemorrhagia about intracranial rupture aneurysm pa-tients before operation, and provide basis for preventing rehaemorrhagia. Methods With retrospective case-control study meth-od, 465 cases of definite intracranial rupture aneurysm patients before operation were investigated by questionnaire. These cases were divided into rehaemorrhagia group （n=113） and non-rehaemorrhagia group （n=352）, and the risk factors of rehaemorrha-gia were screened by single factor and multiple factors methods. Results The incidence rate of intracranial rupture aneurysm pa-tients before operation reached up to 24. 3% （113/465）. Multiple factors logistic regression analysis results showed that these factors such as history of hypertension （OR=4. 092）, complication with cerebral angiospasm （OR=1. 893）, epilepsy （OR=3. 013）, tumor diameter （OR=2. 787）, and moving too early or out-of bed activity of prematurity （OR=4. 179） were all the risk factors of rehaemorrhagia about intracranial rupture aneurysm patients before operation. Conclusion There is still a little high incidence rate of rehaemorrhagia about intracranial rupture aneurysm patients before operation, and it affects the prognosis of these patients. There are many risk factors affecting the incidence rate of rehaemorrhagia, so we should adopt intervention meas-ures to aim directly at these high risk factors.
作者
尚琴芬
杨玲
黄丹红
Shang Qinfen Yang Ling Huang Danhong(Neurosurgical Department of Enze Hospital in Enze Medical Group in Taizhou, 318050, China Taizhou Central Hospital Luqiao Hospital of Enze Medical Group)
出处
《中国医院统计》
2016年第6期424-426,共3页
Chinese Journal of Hospital Statistics
关键词
颅内动脉瘤
破裂动脉瘤
术前
再出血
危险因素
intracranial aneurysm
rupture aneurysm
pre-operation
rehaemorrhagia
risk factor
