摘要
目的探索舒血宁注射液治疗短暂性脑缺血患者的临床疗效及血液学机制。方法回顾性分析短暂性脑缺血患者临床资料92例,按照不同的治疗方案随机分组。对照组46例,给予低分子肝素钙注射液、阿司匹林肠溶片、胞磷胆碱钠注射液进行西医常规治疗;观察组46例在低分子肝素钙和阿司匹林肠溶片治疗的基础上给予舒血宁注射液静滴治疗,观察2组治疗7天后的临床疗效及治疗前后血液学指标变化。结果观察组临床治疗总有效率为91.3%;对照组临床治疗总治愈率82.6%。两组患者临床总有效率比较,差异有显著性意义（χ^2=9.283,P〈0.05）。经过7 d治疗后,2组患者全血高切黏度、全血低切黏度、血浆黏度以及血浆纤维蛋白原均有效下降,且观察组显著好于对照组,差异有统计学意义（P〈0.05）。结论舒血宁注射液可有效改善短暂性脑缺血发作的血液流变学状态,降低血黏度,改善微循环,促进患者康复。
Objective To explore Shuxuening injection in the treatment of patients with transient ischemic clinical effect and mecha-nism of hematology. Methods clinical data of 92 cases of patients with transient cerebral ischemic in our hospital were analyzed. Ac-cording to the different treatment options, they were divided into groups. The control group of 46 cases was given low molecular weight heparin injection, Aspirin, citicoline sodium injection and Western conventional treatment. The observation group of 46 cases was treated with Shuxuening intravenous injection therapy on the basis of low molecular weight heparin and aspirin enteric-coated tablets. The clinical effect for 7 days and blood parameters before and after treatment were observed. Results The clinical total effective rate of the observation group and the control group was 91.3% and 82.6%, respectively, and the difference was significant（ χ^2 =9.283, P〈0.05）. After 7 day＇s treatment, the high shear whole blood viscosity, low shear whole blood viscosity, plasma viscosity and plasma fibrinogen of the two groups were effectively decreased, the observation group was significantly better than the control group,and the difference was significant（ P〈0.05）. Conclusion Shuxuening injection can effectively improve the transient cerebral is-chemic attack hemorheology status, lower blood viscosity, improve microcirculation, and promote the rehabilitation of patients.
出处
《中国中医药现代远程教育》
2016年第23期52-53,共2页
Chinese Medicine Modern Distance Education of China
