摘要
目的观察艾迪注射液联合TP方案化疗治疗晚期非小细胞肺癌的疗效和毒副反应。方法 46例晚期非小细胞肺癌患者随机分为2组,每组各23例,对照组单用TP方案化疗,实验组使用艾迪注射液联合TP方案化疗,比较2组的疗效、生活质量及毒副反应。结果对照组完全缓解2例,部分缓解10例,稳定9例,进展2例,总有效率52.2%;实验组完全缓解3例,部分缓解11例,稳定8例,进展1例,总有效率60.9%,2组疗效相当(P>0.05),但实验组的骨髓抑制、恶心、呕吐等毒副反应的发生率低于对照组,且实验组的生活质量改善情况优于对照组,差异有统计学意义(P<0.05)。结论艾迪注射液联合TP方案治疗晚期非小细胞肺癌能够降低毒副反应,改善患者生活质量,具有应用价值。
Objective To evaluate the therapeutic effect and toxic and side effects of Aidi injection combined with tp regimen in the treatment of advanced non-small cell lung cancer. Methods 46 patients with advanced non-small cell lung cancer were randomly divided into two groups, with 23 cases in each group. Patients in the control group were treated by TP chemotherapy, while patients in the experimental group were treated by Aidi injection combined with TP chemotherapy. The effect, toxicity and quality of life of pa-tients were evaluated. Results In the control group, 2 cases got complete response（CR）, 10 cases were partial response（PR）, 9cases had stable disease（ SD）, and 2 cases had progression disease（ PD）. In the experimental gourp, 3 cases got complete re-sponse（CR）, 11 cases were partial response（PR）, 9 cases had stable disease（SD）, and 1 case had progression disease（PD）.The effects were similar（P〉0.05） in the two groups with the total effective rates of 52.2% and 60.9%, respectively. The incidence of toxicity such as bone marrow suppression, nausea and vomiting of the experiment group was statistically reduced compared with the control group. The quality of life in the experiment group was better than that in the control group（ P〈0.05）. Conclusion The combination of Aidi injection and TP regimen in the treatment of advanced non small cell lung cancer can reduce the toxicity, improve the quality of life of patients, and has application value.
出处
《中国中医药现代远程教育》
2016年第23期94-95,共2页
Chinese Medicine Modern Distance Education of China
关键词
艾迪注射液
晚期非小细胞肺癌
毒副反应
咳喘
Addie injection
advanced non small cell lung cancer
toxic and side effects
cough with asthma
