摘要
目的总结分析不同溶栓效果患者纤维蛋白原及D-二聚体动态变化的影响。方法 50例溶栓治疗患者,根据溶栓治疗效果分为溶栓优良组(28例)和溶栓一般组(22例)。分析两组患者纤维蛋白原及D-二聚体的动态变化。结果在溶栓治疗后6 h,溶栓优良组与溶栓一般组纤维蛋白原含量均达到最低,分别为(0.62±0.32)、(1.56±0.70)g/L,比较差异具有统计学意义(P<0.05)。溶栓优良组与溶栓一般组患者的D-二聚体含量水平达到最高值,分别为(7.52±3.32)、(2.01±1.20)μg/L,比较差异具有统计学意义(P<0.05)。结论溶栓效果较好的患者其纤维蛋白原以及D-二聚体含量的变化更加明显,可为临床预后评价提供重要参考,值得推广应用。
Objective To summarize and analyze influence by different thrombolytic effects in patients on dynamic changes of fibrinogen and D-dimer. Methods A total of 50 patients receiving thrombolysis were divided by their thrombolytic effects into good thrombolysis group（28 cases）and general thrombolysis group（22 cases）. Analysis was made on dynamic changes of fibrinogen and D-dimer in both groups. Results After 6 h of thrombolysis, the good thrombolysis group and general thrombolysis group all had the lowest fibrinogen contents respectively as（0.62±0.32）and（1.56±0.70）g/L, and their difference had statistical significance（P〈0.05）. The good thrombolysis group and general thrombolysis group all had the highest D-dimer contents respectively as（7.52±3.32）and（2.01±1.20）μg/L, and their difference had statistical significance（P〈0.05）. Conclusion Changes of fibrinogen and D-dimer contents are more remarkable in patients with better thrombolytic effect, and it can provide important reference for clinical prognosis. It is worth promoting and applying.
出处
《中国实用医药》
2016年第33期124-125,共2页
China Practical Medicine
