摘要
目的探讨CT灌注参数预测中晚期宫颈癌鳞癌同步放化疗疗效的价值。方法对44例进行为期1年的随访,按照实体肿瘤的RECIST标准将其分为有效组与无效组。对各组的灌注参数进行比较,并采用ROC曲线分析来评价灌注参数预测中晚期宫颈癌同步放化疗疗效的价值。结果 1、BV、PMB在两组间差异有统计学意义(t=3.667,P=0.001;t=3.047,P=0.004),并且有效组的BV值、PMB值较无效组高;BF、MTT、TTP在两组间没有统计学意义。2、经ROC曲线分析,BV的曲线下面积较PMB曲线下面积大,所以BV的评价效能较PMB高。结论 CT灌注成像在中晚期宫颈鳞癌同步放化疗疗效评价方面有预测价值。
Objective To evaluate the value that CT perfusion parameters to predict the response of synchronons radiocllemotherapy for middle-advanced cervical squanmus cancer. Methods 44 patients with cervical squamous cancer later than stage ⅡB were included in this study.They were followed up for 1 year. According to the RECIST, patients were divided into the responders group and non-responders group. Perfusion parameters of the two groups were compared. The perfusion parameters that may be effective were analysed by using ROC curve. Results 1.There were significant difference between two groups in BV and PMB. The BV and PMB in patients who received effective response were greater than patients in other groups. There were no significant difference in BF and MTT and TTP between two groups. 2.Analysed by ROC curve, the area under curve of BV were bigger than that of PMB. It counld conclude the diagnostic potency of BV higher than that of PMB. Conclusion CT perfilsion could predict the response of synchronous radiochemotherapy for middle-advanced cervical squamous cancer.
作者
余莹莹
文智
韩文广
周永
YU Ying-ying WEN Zhi HAN Wen-guang et al.
出处
《中国CT和MRI杂志》
2017年第2期73-76,共4页
Chinese Journal of CT and MRI
关键词
宫颈癌
同步放化疗
CT灌注成像
疗效评价
Cervical Cancer
Synchronous Radiochemotherapy
CT Perfusion
Response Evaluation
