摘要
通过UV、IR、1H NMR、13C NMR、MS、TG、DSC等指纹图谱特征,对芦丁的结构、成分及特性进行了解析。结果表明,在255nm和375nm有两个最大紫外吸收峰;红外吸收峰分别是:羰基υC=O1655.03cm^(-1),苯环骨架振动频率υC=C1603.69cm^(-1),羟基υ-OH3423.42cm-1;1H NMR谱中主要氢原子的归属:δ12.48(5-OH)、10.77(7-OH)、9.35(4′-OH)、9.29(3′-OH);13C NMR归属δ178.0(C-4),164.6(C-7),161.5(C-9),157.9(C-5),157.1(C-2);加热经过三次失重,样品结构发生完全分解;质谱提供了基本裂解途径。为芦丁及其衍生物的研究生产和质量控制提供可靠的指纹图谱数据。
The structure, composition and characteristics of rutin are analyzed by fingerprint spectrum, such as UV, IR, ^1H-NMR, ^13C-NMR, MS, TG and DSC etc. There are two maximum UV absorption peaks at 255 and 375nm respectively; the infrared absorption peaks are showed as follows： carbonyl υC=O1655.03cm^-1, benzene ring skeleton vibration frequency υC=C1603.69cm^-1 and hydroxyl υ-OH3423.42cm^-1. The attribution of major hydrogen atoms in ^1H NMR spectrum are showed as follows： 812.48 （5-OH）, 10.77 （7-OH）, 9.35 （4＇-OH） and 9.29 （3＇-OH）; and the attribution of ^13C NMR are showed as follows： 8178.0（C-4）, 164.6（C-7）, 161.5（C-9）, 157.9（C-5）, 157.1（C-2）. After thermal weight loss for 3 times, the structure of sample decomposes completely and the mass spectrum provided a basic decomposing way. The analysis provides a reliable fingerprint spectrum data for the research, production and quality control of rutin and its derivatives.
出处
《化学与粘合》
CAS
2017年第1期72-76,共5页
Chemistry and Adhesion
关键词
黄酮
芦丁
热分析
指纹图谱
质量控制
Flavonoids
rutin
thermal analysis
fingerprint spectrum
quality control
