摘要
目的运用能谱CT冠状动脉成像(CTA)评估颈动脉粥样硬化斑块与急性缺血性脑卒中的关系。方法 60例急性缺血性脑卒中患者作为病例组,45例非卒中患者作为对照组。入院后48 h内使用能谱CT行颈动脉CT血管成像检查,检测颈动脉粥样硬化斑块发生率、斑块类型。结果两组患者危险因素的比较,结果显示高血压病、冠心病与急性缺血性脑卒中相关(P<0.05)。两组患者共检出144块斑块,纤维斑块71块(49.3%),脂质斑块54块(37.5%),斑块内出血19块(13.2%)。三种斑块的曲线斜率和有效原子序数大小关系呈现为纤维斑块>斑块内出血>脂质斑块(P<0.05)。病例组52例(86.7%)患者检出斑块,对照组11例(24.4%)检出斑块,两组患者检出斑块比例差异有统计学意义(P<0.05)。病例组颈动脉狭窄例数比例高于对照组,差异有统计学意义(P<0.05)。病例组和对照组稳定斑块和不稳定斑块差异显著(P<0.05)。结论能谱CTA检查可获取颈动脉粥样硬化清晰图像、能谱曲线和高效原子序数,准确分析斑块成分。颈动脉粥样硬化斑块与急性缺血性脑卒中的关系密切。
Objective To evaluate relationship between carotid atherosclerostic plaque and acute ischemic stroke by applying energy spectrum CT coronary angiogram imaging（CTA）. Methods There were 60 patients with acute ischemic stroke as medical cases group and 45 patients without stroke as control group. They received energy spectrum CT coronary angiogram imaging examination within 48 h after admission for incidence of carotid atherosclerostic plaque and plaque types. Results Comparison of risk factors between the two groups showed hypertension and coronary heart disease were correlated with acute ischemic stroke（P〈0.05）. There were totally 144 detected plaques in the two groups, with 71 fibrous plaques（49.3%）, 54 lipid plaques（37.5%） and 19 cases with intraplaque hemorrhage（13.2%）. Rate of curve and effective atomic number relationship in the three plaques were all shown as fibrous plaque 〉 intraplaque hemorrhage 〉 lipid plaque（P〈0.05）. There were 52 cases（86.7%） with detected plaque in the medical cases group and 11 cases（24.4%） in the control group, and their difference of plaque detection rate had statistical significance（P〈0.05）. The medical cases group had more cases with carotid artery stenosis than the control group, and the difference had statistical significance（P〈0.05）. The difference of stable plaque and unstable plaque between the medical cases group and the control group had statistical significance（P〈0.05）. Conclusion Energy spectrum CTA can provide clear image of carotid atherosclerosis, spectrum curve, effective atomic number, and accurate analysis of plaque components. Carotid atherosclerostic plaque is closely correlated with acute ischemic stroke.
出处
《中国实用医药》
2016年第34期4-6,共3页
China Practical Medicine
基金
佛山市卫生和计生局医学科研课题(项目编号:2015138)
