摘要
目的探讨经皮椎体后凸成形术(PKP)治疗老年骨质疏松性椎体压缩性骨折(OVCF)的临床疗效。方法回顾性分析2013年1月~2016年6月收治的200例老年OVCF患者作为研究对象,根据患者接受的不同治疗方法分为经皮椎体成形术(PVP)组100例和PKP组100例。比较两组患者术前骨折椎体压缩度、术后椎体高度恢复率、术后末次随访椎体高度丢失率、骨水泥渗漏发生率、相邻椎体再骨折发生率及术前术后视觉模拟评分(VAS)和功能障碍指数(ODI)。结果 PVP组2例出现神经根症状加重,发生肺栓塞1例。两组均无脊髓损伤、感染等并发症发生。所有患者均获随访6~39个月[(17.6±5.7)个月]。两组手术时间、失血量及骨水泥注入量比较,差异均无统计学意义(P>0.05);PKP组患者椎体压缩程度和椎体高度恢复率明显优于PVP组,且比较差异均有统计学意义(P<0.05);两组间术前、术后时VAS与ODI比较,差异均无统计学意义(P>0.05)。两组内各术前与术后VAS、ODI比较,差异均有统计学意义(P<0.05)。结论 PKP和PVP治疗OVCF均可缓解患者疼痛和提高活动功能。但PKP术后对于患者脊柱生理解剖位置的恢复优于PVP组。
Objective To explore the clinical efficacy of percutaneous kyphoplasty in treatment of osteoporotic vertebral compression fractures. Methods 200 cases of OVCF elderly patients cured in our hospital from January 2013 to June 2016 were selected as the study objects. According to the choice of patients with different surgical methods, they were divided into PVP group （pereutaneous vertebroplasty group） and PKP group with 100 cases in each. Vertebral compression fracture degree before surgery, vertebral height restoration rate after the end of the follow-up rate of vertebral height loss, bone cement leakage incidence of adjacent vertebral bodies and then fracture incidence before and after surgery visual analog scale （VAS） and disability index （ODI） were compared. Results There were 2 cases with nerve root symptoms, and 1 case with pulmonary embolism in PVP group. There were no spinal cord injury, infection and other complications in both groups. All patients were followed up for 6 to 39 months [（17.6 ± 5.7） months]. There were no statisticcal significances between the two groups on operative time, blood loss and bone cement injection amount （P 〉 0.05）. Vertebral compression and restore vertebral height of PKP group were significantly better than those of PVP group, and the difference was statistically significant （P 〈 0.05）. There were no statistical sii^aificances between the two groups on postoperative VAS and ODI before surgery （P 〉 0.05）. Within each of the two groups before surgery and postoperative VAS, ODI, the difference was statistically significant （P 〈 0.05）. Conclusion PKP and PVP in treatment of OVCF can alleviate patient pain and improve functional activity. But restoration of spinal anatomy and physiology of the patient position after surgery of PKP group is better than PVP group.
出处
《中国医药科学》
2016年第20期190-193,共4页
China Medicine And Pharmacy
