摘要
目的:观察匹多莫德在小儿变应性鼻炎伴发哮喘治疗中的应用效果。方法:选取河北钢铁集团宣钢职工医院儿科2013年1月~2015年1月期间确诊的变应性鼻炎伴哮喘患儿60例,采用随机数字表法将其分为治疗组及对照组,各30例,2组患儿均给予常规联合舌下免疫治疗,治疗组在上述基础上加用匹多莫德口服,观察治疗过程中2组患儿免疫功能、炎症因子水平及肺功能改善情况。结果:治疗组患儿免疫功能、炎症因子水平及肺功能改善均明显优于对照组(P<0.05)。结论:匹多莫德能显著提高变应性鼻炎伴哮喘患儿免疫功能,减轻炎症反应,促进肺功能改善,疗效确切。
Objective：To observe the application effect of pidotimod in the treatment of allergic rhinitis in children accompanied by allergic asthma.Methods：A total of 60 children with allergic rhinitis accompanied by allergic asthma who were admitted in our hospital from January,2013 to January,2015 were included in the study and randomized into the treatment group and the control group with 30 cases in each group.The patients in the two groups were given routine treatments in combined with sublingual immunotherapy.On this basis,the patients in the treatment group were given additional pidotimod.The immunological function,inflammatory cytokine level,and pulmonary function improvement in the two groups were observed.Results：The immunological function,inflammatory cytokine level,and pulmonary function improvement in the treatment group were significantly superior to those in the control group（P〈0.05）.Conclusions：Pidotimod can significantly enhance the immunological function in children with allergic rhinitis in children accompanied by allergic asthma,alleviate the inflammatory reaction,and promote the pulmonary function improvement,with an accurate efficacy.
作者
赵霞
ZHAO Xia(Xuangang Worker＇s Hospital of Iron and Steel Group, Zhangjiakou 075100, Hebel, China)
出处
《海南医学院学报》
CAS
2017年第4期563-565,共3页
Journal of Hainan Medical University
基金
河北钢铁集团科学技术获奖项目(2013019204)~~
关键词
小儿变应性鼻炎
变应性哮喘
匹多莫德
舌下免疫治疗
Allergic rhinitis in children
Allergic asthma
Sublingual immunotherapy
Pidotimod
Efficacy
