摘要
背景:目前的椎间融合器发展迅速,很多融合器已经应用于临床,有些还处于实验阶段,各种融合器的特点鲜明,优缺点明显。目的:阐述椎间融合器的发展历程,对各种类型的融合器进行详细分析,以期为以后的融合器发展做出相应的指导作用。方法:第一作者应用计算机检索1989年1月至2016年3月Pub Med数据库、中国知网的相关文章,英文检索词"interbody fusion cage,PEEK,TMC";中文检索词"椎间融合器,聚醚醚酮融合器,钛网"。共检索到106篇相关文献,38篇文献符合纳入标准。结果与结论:在椎体间进行椎体融合是目前治疗脊柱退行性疾病的主要方法之一。目前在临床上使用的椎间融合器种类繁多,如钛网融合器、聚醚醚酮融合器、可吸收融合器等。融合器中可采用的移植物也多种多样,如自体骨、异体骨、合成骨、骨形态发生蛋白等。文章详细的描述了椎间融合器的发展历程,并着重阐述了临床上常用的椎间融合器,对未来椎间融合器的前景做出了估计,最后对椎间融合器的发展表达了自己的看法。
BACKGROUND： With the rapid development of technology, most interbody fusion cages have been applied in clinic, but some are still in experimental stage. All fusion cages hold their own distinct characteristics as well as advantages and shortcomings.OBJECTIVE： To clarify the development course of interbody fusion cages and analyze their types in detail, thereby paving ways for its improvement. METHODS： A computer-based search for literatures in CNKI and Pub Med databases published from January 1989 to March 2016 was performed using the keywords of ＂interbody fusion cage, PEEK, TMC＂ in English and Chinese, respectively. A total of 106 articles were retrieved and 38 articles were in accordance with the inclusion criteria. RESULTS AND CONCLUSION： Intervertebral fusion is a major method to treat spinal degenerative diseases. There are a variety of fusion cages in clinic, such as pyramesh, polyetheretherketone and absobable fusion cages. Implants used for fusion cages include autogenous, allogenic and artificial bones as well as bone morphogenetic protein. We introduce the development process of fusion cages in detail, emphasize the commonly used fusion cages and analyze its development in future. In the end, we give our opinions about the development of intervertebral fusion cages.
出处
《中国组织工程研究》
CAS
北大核心
2017年第2期315-321,共7页
Chinese Journal of Tissue Engineering Research
