摘要
呼出气一氧化氮检测可反映气道嗜酸性粒细胞性炎症，近年来被广泛用于辅助支气管哮喘的诊断、监测支气管哮喘患者气道炎症以及监测患者对治疗效果的反应。呼出气一氧化氮检测作为一种无创性检查，能够得到成人及5岁以上儿童的高度配合，但在5岁以下儿童中的应用存在很多问题，目前国内尚缺乏婴幼儿及新生儿呼出气一氧化氮检测的正常值及相关大样本研究。该文主要从儿童呼出气一氧化氮检测的原理及方法、正常参考值、影响因素、临床应用等方面进行综述。
Exhaled nitric oxide fraction （FeNO）reflects eosinophilic bronchial inflammation, and has been widely used to assist in the diagnosis of asthma,to monitor the airway inflammation and the responce to treatment effects of asthma in recent years. FeNO as a noninvasive examination, obtains a high degree of cooperation in adults and children over 5 years of age, but there are a lot of problems in children under 5 years of age. At present, there is still a lack of normal values and large sample-sized studies of FeNO in infants and neonates in China. The principle and method, normal reference value, influencing factors, clinical application and so on of exhaled nitric oxide detection are reviewed in this paper.
作者
刘丹
魏兵
Liu Dan Wei Bing(Joint Training Base of the General Hospital of Shenyang Military Area Command, Jinzhou Medical University, Shenyang 110016, China)
出处
《国际儿科学杂志》
2017年第1期44-46,51,共4页
International Journal of Pediatrics
关键词
呼出气一样化氮
儿童
气道炎症
影响因素
Exhaled nitric oxide fraction
Children
Bronchial inflammation
Influencing factor
