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格列美脲联合二甲双胍治疗糖尿病的临床疗效观察 被引量:2

Clinical Observation of Glimepiride Combined With Metformin in Treatment of Diabetes
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摘要 目的探讨格列美脲联合二甲双胍治疗糖尿病的临床疗效。方法选取2015年6月-2016年6月我院就诊的糖尿病患者128例,随机分为两组,对照组64例,给予二甲双胍治疗,观察组64例,给予格列美脲联合二甲双胍治疗,比较两组血糖、血脂控制效果,并统计其不良反应发生情况。结果观察组治疗后FPG、2 h PG、Ab Hlc水平和TC、TG、LDL-C水平均低于对照组(P<0.05);HDL-C水平高于对照组(P<0.05);不良反应发生率低于对照组(P<0.05)。结论对糖尿病患者采取格列美脲联合二甲双胍治疗的效果较好,有效控制患者血糖,且用药安全。 Objective To explore the clinical efficacy of glimepiride combined with metformin in the treatment of diabetes. Methods 128 patients with diabetes were randomly divided into two groups from June 2015 to June 2016, the control group(64 cases) was given metformin, the observation group(64 cases), was given glimepiride combined with metformin. Compared blood sugar, blood lipid control effect, and adverse reaction occurred of the two groups. Results The levels of FPG, 2 h PG, Ab Hlc and TC, TG, LDL-C in the observation group were lower than those in the control group(P〈0.05); HDL-C level was higher than that in the control group(P〈0.05), incidence of adverse reactions was lower than that of the control group(P〈0.05). Conclusion Glimepiride combined with metformin is effective in the treatment of diabetic, and is effective in controlling blood sugar in patients with diabetes.
作者 吴承伟
出处 《中国卫生标准管理》 2017年第3期84-85,共2页 China Health Standard Management
关键词 糖尿病 格列美脲 二甲双胍 diabetes glimepiride metformin
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