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胎儿生长受限新生儿脐血血气分析及其临床意义 被引量:5

Umbilical cord blood gas analysis and its clinical significance in neonates with fetal growth restriction
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摘要 目的研究并探讨脐血血气分析在胎儿生长受限新生儿中的临床意义。方法于2015年6月~2016年6月,选取证实为胎儿生长受限的新生儿80例作为此次研究的对象,根据分娩方式将其分为A组(顺产)、B组(剖宫产),另选取同时期无生长受限的40例顺产新生儿和40例剖宫产新生儿作为参照对象,将其分别设置为C组、D组。采集所有新生儿的脐动脉血作为标本,对其进行血气分析,比较四组新生儿的脐动脉血PH值、PO_2、PCO_2、BE、HCO_3水平。结果 A组与B组相比,A组新生儿的PH值、BE、HCO_3水平均明显低(P〈0.05);A组与C组相比,A组新生儿的PH值、BE、HCO_3水平均明显低(P〈0.05);B组与D组相比,B组新生儿的BE水平明显低(P〈0.05),PCO_2明显高(P〈0.05);C组与D组相比,C组新生儿的BE水平明显低(P〈0.05),PCO_2明显高(P〈0.05)。结论脐血血气分析是评估新生儿缺氧严重程度的客观指标,对新生儿预后有指导意义。不同分娩方式对新生儿脐血血气值有影响,阴道试产耐受性差,为改善母婴结局,胎儿生长受限尤其是合并高危因素者可适当放宽手术指征。 Objective To study and discuss the clinical significance of umbilical cord blood gas analysis in fetal growth restriction.Methods In June 2015 to June 2016,80 cases of neonatal who confirmed for fetal growth limited were selected as the research object,according to the mode of delivery,they were divided into group A(delivery),group B(cesarean section),at the same period,40 cases of delivery neonates and 40 cases of cesarean section who no growth restriction were selected as reference object,and they were set into group C,group D.The umbilical artery blood samples were collected as the samples,and carried on blood gas analysis,the p H,PO_2,PCO_2,BE and HCO_3 levels of umbilical artery blood were compared between the four groups.Results Compared between group A and group B,the p H,BE and HCO_3 of group A were significantly lower(P〈0.05);compared between group A and C group,the p H,BE and HCO_3 of group A were significantly lower(P〈0.05);compared between group B and group D,the BE of group B was significantly lower(P〈0.05),PCO_2 was significantly higher(P〈0.05);compared between group C and group D,BE of group C was significantly lower(P〈0.05),PCO_2 was significantly higher(P〈0.05).Conclusion Umbilical cord blood gas analysis is an objective index to evaluate the severity of neonatal hypoxia,has guiding significance for the prognosis of the newborn.Different modes of delivery has influence on the index of umbilical cord blood gas in newborn,the tolerance of vaginal delivery is terrible,in order to improve maternal and neonatal outcomes,the limited fetal growth,especially combined with high risk factors may be appropriate to relax the operation indications.
作者 龚明霞 杜丹
出处 《中国医药科学》 2016年第22期60-63,共4页 China Medicine And Pharmacy
关键词 胎儿生长受限 脐血 血气分析 分娩方式 Fetal growth restriction Umbilical cord blood Blood gas analysis Delivery mode
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