摘要
目的：分析卡前列甲酯栓联合卡前列素氨丁三醇治疗宫缩乏力性产后出血的治疗效果。方法选取120例宫缩乏力性产后出血，采取随机数字表法分为对照组与观察组，每组各60例，对照组给予卡前列甲酯栓治疗，观察组在对照组基础上加用卡前列素氨丁三醇治疗，比较两组患者产后2 h、产后12 h出血量、临床治疗情况及不良发应。结果观察组与对照组相比止血起效时间缩短，产后2 h内出血量及产后12 h内出血量均减少，差异均有统计学意义（t＝4．56、5.92、6．12，均P＜0．05）。对照组临床总有效率为73．33％，观察组临床总有效率为91．67％，两组临床总有效率差异有统计学意义（χ2＝6．12，P＜0．05）。观察组与对照组相比消化道症状、一次性血压波动、颜面潮红、产褥期感染发生率均较低，差异均有统计学意义（χ2＝4．71、4.98、4．34、5．43，均P＜0．05）。结论卡前列甲酯栓联合卡前列素氨丁三醇治疗宫缩乏力性产后出血的临床效果显著，产后出血量少，治疗情况较好，不良反应发生率低，安全性更高。
Objective To analyze the effect of carboprost methylate suppository combined with romethamine in the treatment of postpartum hemorrhage in contractions fatigue.Methods 120 cases of postpartum hemorrhage contractions fatigue were randomly divided into control group and observation group,60 cases in each group.The control group was given carboprost methylate suppository treatment,the observation group was given romethamine com-bined with carboprost methylate suppository.The 2h,12h postpartum blood loss,clinical treatment effect and adverse reaction were compared between the two groups.Results Compared with the control group,the hemostatic time of the＆amp;nbsp;observation group shortened,postpartum haemorrhage amount within 2h and postnatal within 12h blood loss of the observation group were reduced,the differences were statistically significant （t=4.56,5.92,6.12,all P〈0.05）.The total effective rate of the control group was 73.33%,which was significantly lower than 91.67% of the observation group,the difference was statistically significant （χ2 =6.12,P 〈0.05 ）.Compared with the control group,the incidence rates of digestive tract symptoms,disposable blood pressure fluctuations,facial blushing,puerperal infection in the observation group were lower,the differences were statistically significant （χ2 =4.71,4.98,4.34,5.43,all P〈0.05）.Conclusion The clinical effect of carboprost methylate suppository combined with romethamine in the the treatment of contractions fatigue postpartum hemorrhage is remarkable,with less postpartum haemorrhage amount, better treatment effect,low incidence of adverse reactions and higher security.
出处
《中国基层医药》
CAS
2017年第2期231-234,共4页
Chinese Journal of Primary Medicine and Pharmacy
