摘要
目的:观察症状性大脑中动脉(MCA)缺血患者脑血管储备能力(CVR)的变化,探讨其相关影响因素。方法:收集症状性MCA缺血患者50例为观察组,同时选取健康成年人50例为对照组。比较2组CVR的差异,分析不同临床病理特征的MCA患者CVR能力的差异,分析影响MCA患者CVR能力的因素。结果:观察组的CVR明显低于对照组,有显著性差异(t=6.276,P<0.001);年龄≥65岁、合并高血压、合并高脂血症、有吸烟史的症状性MCA患者其CVR较低;多因素分析显示,合并高脂血症、合并高血压和吸烟史是影响患者CVR能力的因素。结论:症状性MCA缺血患者CVR较低,且与患者是否合并高脂血症、高血压、吸烟史密切相关。
Objective： To observe the changes of cerebral vascular reserve （CVR） capacity in patients with symptomatic middle cerebral artery （MCA） ischemia and analyze the related factors. Methods： Total 50 patients with symptomatic MCA ischemia were enrolled as observation group, and 50 healthy adults were enrolled as control group. The difference in CVR between the two groups were compared. The difference in CVR capacity of MCA patients with different clinical pathological features were further analyzed. The factors affecting CVR capacity in patients with MCA were analyzed. Results： The CVR of the patients in the observation group was significantly lower than that in the control group （t=6.276, P〈0.001）. Symptomatic MCA patients with age≥65 years, hypertension, hyperlipidemia, smoking and presented lower CVR. Multivariate analysis showed that the combination of hyperlipidemia, hypertension and smoking were the factors influencing CVR capacity. Conclusion： Patients with symptomatic MCA ischemia have obvious lower CVR, which were strongly associated with hyperlipidemia, hypertension, and smoking.
出处
《神经损伤与功能重建》
2017年第1期25-27,共3页
Neural Injury and Functional Reconstruction
关键词
症状性大脑中动脉缺血
脑血管储备能力
多重逐步回归
影响因素
symptomatic middle cerebral artery ischemia
cerebrovascular reserve capacity
multiple stepwise regression
influencing factors
