摘要
目的探讨美托洛尔与卡维地洛治疗慢性心力衰竭的临床效果。方法 50例慢性心力衰竭患者作为研究对象,随机分为观察组和对照组,每组25例。观察组行卡维地洛治疗,对照组行美托洛尔治疗。对比两组治疗效果。结果治疗后,观察组心功能分级、肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)均低于对照组,差异均具有统计学意义(t=3.1009、3.9428、2.8927,P<0.05)。结论在慢性心力衰竭的治疗中,卡维地洛的效果优于美托洛尔,具有一定的实用价值,值得在临床实践中借鉴并推广。
Objective To explore clinical effect of metoprolol and carvedilol in the treatment of chronic cardiac failure. Methods A total of 50 chronic cardiac failure patients as study subjects were randomly divided into observation group and control group, with 25 cases in each group. The observation group receive carvedilol for treatment, and the control group received metoprolol for treatment. Curative effect was compared in two groups. Results After treatment, the observation group had lower cardiac functional grading,tumor necrosis factor-α（TNF-α） and interleukin-6（IL-6） than the control group, and differences had statistical significance（t=3.1009, 3.9428, 2.8927, P〈0.05）. Conclusion Carvedilol shows better curative effect than metoprolol in the treatment of chronic cardiac failure with certain practical value, and it is worth reference and promotion in clinical practice.
出处
《中国现代药物应用》
2017年第1期92-94,共3页
Chinese Journal of Modern Drug Application
