摘要
目的观察并分析门冬胰岛素30联合二甲双胍在老年初诊2型糖尿病临床治疗中的效果。方法 50例老年初诊2型糖尿病患者作为分析对象,对全部患者实施门冬胰岛素30联合二甲双胍治疗,比较并分析患者治疗前后临床指标的变化情况。结果治疗前患者空腹血糖为(13.5±1.8)mmol/L、糖化血红蛋白为(10.2±0.7)%、甘油三酯(TG)为(2.95±1.20)mmol/L、低密度脂蛋白胆固醇(LDL-C)为(3.85±1.14)mmol/L,均高于治疗后的(6.3±1.1)mmol/L、(6.3±0.6)%、(1.58±0.95)mmol/L、(2.16±0.85)mmol/L,差异均具有统计学意义(P<0.05);治疗前后体质量比较差异无统计学意义(P>0.05)。本次不良反应发生率为24%。结论针对老年初诊2型糖尿病临床患者而言,实施门冬胰岛素30联合二甲双胍治疗具有显著效果,可以改善患者的临床症状,有效降低血糖和不良反应的产生,在临床应用中具有可行性,可进行广泛的推广及使用。
Objective To observe and analyze clinical effect of insulin aspart 30 combined with melbine in the treatment of type 2 diabetes mellitus. Methods A total of 50 newly diagnosed elderly type 2 diabetes mellitus patients as analyzed subjects all received insulin aspart 30 combined with melbine for treatment. Clinical indexes changes before and after treatment were compared and analyzed. Results Before treatment, patients had fasting blood glucose as（13.5±1.8） mmol/L, glycosylated hemoglobin as（10.2±0.7）%, triglyceride（TG） as（2.95±1.20） mmol/L and low density lipoprotein cholesterin（LDL-C） as（3.85±1.14） mmol/L, which were all higher than（6.3±1.1） mmol/L,（6.3±0.6）%,（1.58±0.95） mmol/L and（2.16±0.85） mmol/L after treatment, and differences had statistical significance（P〈0.05）. There was no statistically significant difference in body mass before and after treatment（P〉0.05）. Adverse reaction rate was 24% in this study. Conclusion Insulin aspart 30 combined with melbine shows significant effect in the treatment of newly diagnosed elderly type 2 diabetes mellitus, which can improve clinical symptoms of patients and decrease occurrence of blood glucose and adverse reaction. This method has feasibility in clinical application and can be widely promoted and applicated.
出处
《中国现代药物应用》
2017年第1期100-101,共2页
Chinese Journal of Modern Drug Application
关键词
老年初诊2型糖尿病
门冬胰岛素30
二甲双胍
Newly diagnosed elderly type 2 diabetes mellitus
Insulin aspart 30
Melbine
