摘要
目的浅析微生态制剂在治疗小儿腹泻中的临床应用效果。方法 132例小儿腹泻患儿依据治疗方法不同分为A组和B组,每组66例。两组均给予蒙脱石散治疗,A组加用微生态制剂治疗。对比治疗效果、治疗时间与不良反应情况。结果 A组治愈47例(71.21%)、好转17例(25.76%)、无效2例(3.03%),治疗总有效率为96.97%(64/66);B组治愈33例(50.00%)、好转25例(37.88%)、无效8例(12.12%),治疗总有效率为87.88%(58/66);两组治疗总有效率比较,差异具有统计学意义(P<0.05)。A组平均治疗时间为(4.51±0.84)d,B组的平均治疗时间为(6.97±0.72)d,两组治疗时间比较,差异具有统计学意义(P<0.05)。A组发生皮疹2例(3.03%)、便秘4例(6.06%),不良反应率为9.09%(6/66);B组发生皮疹3例(4.55%)、便秘4例(6.06%),不良反应率为10.61%(7/66);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论在小儿腹泻的治疗过程中加用微生态制剂,可以显著提高疗效,且不良反应少,值得推广。
Objective To briefly analyze clinical application effect by microecologics in the treatment of infantile diarrhea. Methods A total of 132 children with infantile diarrhea were divided by different treatment measures into group A and group B, with 66 cases in each group. Both groups received montmorillonite powder for treatment, while group A received additional microecologics for treatment. Comparison was made on curative effects, treatment time and adverse reactions between the two groups. Results Group A had 47 cured cases（71.21%）, 17 improved cases（25.76%） and 2 ineffective cases（3.03%）, with total effective rate as 96.97%（64/66）. Group B had 33 cured cases（50.00%）, 25 improved cases（37.88%） and 8 ineffective cases（12.12%）, with total effective rate as 87.88%（58/66）. The difference of total effective rate had statistical significance between the two groups（P〈0.05）. Group A had mean treatment time as（4.51±0.84） d, and group B had mean treatment time as（6.97±0.72） d. The difference of treatment time had statistical significance between the two groups（P〈0.05）. Group A had 2 cases（3.03%） with rash and 4 cases（6.06%） with constipation, with incidence of adverse reactions as 9.09%（6/66）. Group B had 3 cases（4.55%） with rash and 4 cases（6.06%） with constipation, with incidence of adverse reactions as 10.61%（7/66）. There was no statistically significant difference of incidence of adverse reactions between the two groups（P〉0.05）. Conclusion Implement of microecologics in treating infantile diarrhea can remarkably improve curative effect, with few adverse reactions. It is worth promoting.
出处
《中国现代药物应用》
2017年第1期124-125,共2页
Chinese Journal of Modern Drug Application
关键词
微生态制剂
小儿腹泻
蒙脱石散
治疗效果
不良反应
Microecologics
Infantile diarrhea
Montmorillonite powder
Curative effect
Adverse reactions
