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卵巢癌筛查的研究进展 被引量:6

Research progress of ovarian cancer screening
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摘要 卵巢癌被认为最致命的癌症之一,但是早期卵巢癌的5年生存率却达90%以上。由于缺乏典型的症状和有效的筛选标准,只有25%左右的卵巢癌患者可以在早期(Ⅰ期)被发现,因此建立卵巢癌的筛查机制具有重大意义。目前卵巢癌筛查的目标人群主要是50岁以上的绝经妇女和遗传性卵巢癌家族的高危人群,筛查方法有血清CA125测定和阴道超声检查,筛查方案包括血清CA125测定、阴道超声检查和血清CA125测定联合阴道超声检查三种。随着对卵巢癌标志物研究的深入、影像学诊断方法的进步,卵巢癌的筛查取得了可喜的进展。 Ovarian cancer is thought to be one of the most lethal cancers, but the 5 year survival rate of early ovarian cancer is over 90%. Due to the lack of typical symptoms and effective screening criteria, only about 25% of patients with ovarian cancer can be found in the early siage ( I stage), so the establishment of ovarian cancer screening system is of great significance. At present, the target population of ovarian cancer screening is mainly menopausal women over 50 years of age and high-risk population of hereditary ovarian cancer families. Screening methods are serum CA125 and transvaginal ultrasound examination. The screening program include the determination of serum CA125, transvagi- nal ultrasound and serum CA125 combined with transvaginal ultrasound examination. With the progress of the research of ovarian cancer markers and imaging diagnosis methods, ovarian cancer screening has made gratifying progress.
作者 陈仲波 朱笕青 CHEN Zhongbo ZHU Jianqing(Department of Gynecologic Oncology, Zhejiang Cancer Hospital, Hangzhou 310022, China)
出处 《中国现代医生》 2016年第35期164-168,共5页 China Modern Doctor
基金 浙江省医药卫生科研基金项目(2017KY248) 浙江省中医药科学研究基金项目(2017ZA035)
关键词 卵巢癌 高危人群 CA125 阴道超声检查 筛查 Ovarian earcer High risk population CA125 Transvaginal ultrasound Screening
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