摘要
目的:研究根据多层螺旋CT测量肿瘤CT值鉴别乏脂肪肾错构瘤与肾癌的价值.方法:回顾性分析苏州大学附属第一医院收治的121例肾脏肿瘤患者的多层螺旋CT资料.分析检测数据,并根据各个指标在ROC曲线下的面积,分析其诊断特异性及敏感性.结果:按常规感兴趣点方法测量,仅平扫期CT平均值在两组间差异有统计学意义(P<0.05),其ROC曲线下面积仅为0.857;按照整个肿瘤大范围方法测量,肿瘤大范围的6个指标比较差异有统计学意义(P<0.05).每个指标的R0C曲线下面积均大于0.857.R0C曲线下面积前三位依次:①大范围平扫期最小值(0.981).②皮质期最小值(0.969).③实质期最小值(0.913).结论:本研究中整个肿瘤大范围测量CT值的方法,可以有效地提高肾脏良恶性肿瘤的诊断与鉴别水平,特别是对于鉴别乏脂肪肾错构瘤与肾癌;肿瘤大范围平扫期最小CT值≤-29 Hu可以作为诊断乏脂肪肾错构瘤、排除肾癌的标准.
AIM: To study the value of multi-slice spiral CT in differentiating minimal fat renal angiomyolipoma and renal cell carcinoma. METHODS: The multi-slice spiral CT data of 121 cases of renal tumor admitted into the First Hospital Affiliated to Suzhou University were retrospectively analyzed. The specificity and sensitivity of diagnosis were analyzed according to the area under the ROC curve of each index. RESULTS : According to the conventional method of point of interest, there was a statistically significant difference between the two groups in the average CT value after plain scanning (P〈 0.05 ), the value of Area under ROC curve is 0. 857. According to the large scale of the whole tumor, there were statistically significant differences between the 6 indexes of tumor in large scale (P〈 0.05 ). The area under the R0C curve of each index was more than 0.857. The area under the ROC curve in the top three were, in order: (1)minimum value of large scale plain scanning( 0.981 ) ; (2)minimum value of cortical phase (0.969) ; (3)minimum value of parenchymal phase ( 0.913 ). CONCLUSION: The method for measuring CT value of whole tumor in large scale in this study can effectively improve the level of diagnosis and differentiation of renal benign and malignant tumors, especially for minimal fat renal angiomyolipoma and renal cell carcinoma. For the plain scanning of a wide range of tumors, the minimum CT value is less than or equal to -29 Hu, which can be used as a diagnostic criteria of minimal fat renal angiomyoli- poma and exclusion of renal cell carcinoma.
作者
赵晓俊
浦金贤
平季根
臧晋
陆勇
席启林
侯文杰
ZHAO Xiao-Jun PU Jin-Xian PING Ji-Gen ZANG fin LU Yong XI Qi-Lin HOU Wen-fie(Department of Urology, the First Hospital Affiliated to Suzhou University, Suzhou 215006, China)
出处
《转化医学电子杂志》
2016年第12期14-17,共4页
E-Journal of Translational Medicine
关键词
CT扫描
肾细胞癌
乏脂肪肾错构瘤
临床鉴别
CT scan
renal cell carcinoma
minimal fat renal angiomyolipoma
differential diagnosis