摘要
目的:探讨补肾壮筋汤治疗肝肾亏虚型膝骨关节炎的临床疗效。方法:将220例膝骨关节炎患者随机分为治疗组和对照组,每组110例。治疗组口服补肾壮筋汤治疗,对照组口服盐酸氨基葡萄糖胶囊治疗。2组均以12周为1个疗程。观察2组及治疗前后疼痛视觉模拟评分法(VAS)评分、西安大略和麦马斯特大学(WOMAC)骨关节炎指数的变化。结果:治疗组完成101例,脱落9例;对照组完成97例,脱落13例。2组脱落率比较,差异无统计学意义(P>0.05)。治疗组优22例,良45例,中20例,差14例,优良率为66.34%,总有效率为86.14%;对照组优16例,良34例,中32例,差15例,优良率为51.55%,总有效率为84.54%。治疗组优良率明显高于对照组(P<0.05);2组总有效率比较,差异无统计学意义(P>0.05)。治疗后,2组VAS评分与WOMAC骨关节炎指数均有明显改善(P<0.01),且治疗组优于对照组(P<0.05)。结论:补肾壮筋汤能有效缓解肝肾亏虚型膝骨关节炎的临床症状,改善关节功能。
Objective：To investigate the clinical efficacy of Bushen Zhuangjin Tang （补肾壮筋汤） in the treatment of liver-kidney deficiency type knee osteoarthritis.Methods：Two hundred and twenty cases of knee osteoarthritis were randomly divided into a treatment group and a control group,110 cases in each.The treatment group was treated with Bushen Zhuangiin Tang, while the control group was treated with Glucosamine Hydrochloride Capsules.Both groups were treated for 12 weeks,observing the clinical curative effect,and the changes of the VAS scores,the WOMAC osteoarthritis index before and after treatment.Results：The treatment of 101 cases in the treatment group was completed,and nine of them were not,while in the control group,97 cases＇ treatment was completed and 13 cases were not.The results showed that there were no significant differences between the two groups （ P 〉 0.05 ） .In the treatment group,22 cases were excellent,45 cases were good,20 cases were mediocre,and 14 eases were not good,the excellent and good rate being 66.34% and the total effective ratebeing 86.14%.In the control group,16 cases were excellent,34 cases were good,32 cases were mediocre and 15 cases were not good, the excellent and good rate being 51.55% and the total effective rate being 84.54%. The excellent and good rate of the treatment group was significantly higher than that of the control group （P 〈 0.05 ） .There wasno significant difference in the total effective rate between the two groups （P 〉 0.05 ） .After treatment,the VAS score and WOMAC osteoarthritis index of the two groups were significantly improved （P 〈 0.01 ） ,and the treatment group was better than the control group （P 〈 0.05 ） .Conclusion：Bushen Zhuangjin Tang can effectively alleviate the clinical symptoms of liver-kidney deficiency type knee osteoarthritis and improve joint function
出处
《风湿病与关节炎》
2017年第2期15-17,52,共4页
Rheumatism and Arthritis
基金
福建省自然科学基金(2016J01395)
福建省中青年教师教育科研项目新世纪优秀人才(JA14150)
福建中医药大学校管课题-科研创新平台专项(X2015021-平台)
关键词
骨关节炎
膝
补肾壮筋汤
肝肾亏虚
补肾柔肝
软骨退变
osteoarthritis,knee
Bushen Zhuangjin Tang （补肾壮筋汤 ）
deficiency of liver and kidney
tonifying kidney and liver
cartilage degeneration
