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头痛宁联合氟桂利嗪治疗无先兆偏头痛150例 被引量:5

One Hundred and Fifty Cases of Migraine Without Aura Treated with Toutongning in Combination with Flunarizine
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摘要 目的:观察头痛宁联合氟桂利嗪治疗无先兆偏头痛的临床疗效。方法:选取2013年3月—2015年2月三亚市人民医院神经内科门诊治疗的无先兆偏头痛患者253例,按随机数字表法分为观察组150例和对照组103例。观察组给予头痛宁联合氟桂利嗪治疗,对照组给予氟桂利嗪治疗。结果:观察组治愈率、显效率、总有效率均优于对照组(P<0.05或P<0.01);观察组治疗后头痛发作次数、每次发作持续时间及程度优于对照组(P<0.01);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:头痛宁联合氟桂利嗪治疗无先兆偏头痛临床疗效确切。 Objective: To observe the clinical curative effect of Toutongning (TTN) in combination with flunarizine on migraine without aura. Methods: Two hundred and fifty-three patients with migraine without aura who were treated in Department of Neu- rology of Sanya people s Hospital between March of 2013 and Feb. of 2015 were chosen as the research subjects, and divided into the observation group and the control group according to random number table method, with 150 and 103 cases respectively in each group. The ones in the control group were givern flunarizine for treatment, while the ones in the observation group were add- ed TIN based on the treatment of the control group. Results: The observation group's cure rate, obvious efficacy and total effec- tive rate were all better than those of the control group (P 〈 0.05 or P 〈 0. 01 ). After the treatment, the observation group's headache attack frequency, duration of each episode and the degree of headache were all better than those of the control group. The difference in incidence of adverse reactions between the two groups had no statistical significance ( P 〉 0.05 ). Conclusion : TTN in combination with flunarizine has a remarkable clinical curative effect on migraine without aura.
出处 《河南中医》 2017年第2期248-250,共3页 Henan Traditional Chinese Medicine
关键词 无先兆偏头痛 头痛宁 氟桂利嗪 migraine without aura Toutongning(TTN) flunarizine
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