摘要
炎症反应是腹部手术创伤的重要病理生理变化,适度炎症反应对创伤愈合起到积极作用,但过度炎症反应对机体有害,是术后各种并发症的主要原因,是发展至多器官障碍综合征的共同通路.因此,对围手术期过度炎症反应积极进行干预,可以减少术后并发症发病率和死亡率.但目前对围手术期过度炎症反应的病理生理过程的认识尚处初级阶段.本文对腹部外科围手术期过度炎症反应的诱发因素、发生机制、病理生理变化及对机体的危害和影响进行系统介绍.
Inflammation is an important pathophy-siological change in the perioperative period of abdominal surgery. Moderate inflammatory plays a positive role in wound healing, but excessive inflammation is harmful to the body and is a major cause of postoperative complications and the common pathway of multiple organ dysfunction syndrome. Therefore, intervention of excessive inflam-mation response in the perioperative period can reduce the morbidity and mortality of patients. However, the current understanding of the pathophysiological process of excessive inflammatory response during the perioperative period is still in the primary stage. This article systematically reviews the induced factors, mechanism and pathophysiological changes of excessive inflammatory response during the perioperative period of abdominal surgery as well as its harm to and influence on the body.
出处
《世界华人消化杂志》
CAS
2017年第2期178-184,共7页
World Chinese Journal of Digestology
关键词
腹部外科
围手术期
过度炎症反应
多器官功能障
Abdominal surgery
Perioperative period
Excessive inflammatory response
Multiple organ dysfunction
