摘要
目的 :探讨用尿毒清颗粒治疗慢性肾功能不全的临床效果。方法 :将我院收治的98例慢性肾功能不全患者随机分为观察组与对照组。对对照组患者进行常规治疗,为观察组患者在此基础上使用尿毒清颗粒进行治疗,然后对比分析两组患者的临床疗效及发生不良反应的情况。结果 :与对照组患者相比,观察组患者在进行治疗后其Scr的含量、BUN的含量及24h尿蛋白定量均较低,其CCr较高,差异有统计学意义(P<0.01)。两组患者不良反应的发生率相比较差异无统计学意义(P>0.05)。结论 :为慢性肾功能不全患者应用尿毒清颗粒进行治疗可取得令人满意的效果,能有效改善其肾功能,而且安全性较高。
Objective： To investigate the effects of uremic clearance granule on renal function of patients with chronic renal insufficiency. Methods： Ninety-eight cases of patients with chronic renal insufficiency were randomly divided into observation group and control group, forty-nine cases in each group. The patients of control group were treated with routine method, The patients of observation group were treated with uremic clearance granule on this basis. The renal function, curative effect and untoward effect were compared between the two groups. Results： After treatment, the serum creatinine, blood urea nitrogen and 24 h urinary protein quantitation of observation group patients were evidently lower than those in control group（P 〈0.01）. The endogenous creatinine clearance rate of observation group patients was notably higher than that in control group（P 〈0.01）. The total effective rate of treatment in observation group patients was obviously higher than that of control group（P〈0.01）. There was no significant difference in the rate of untoward effect between the two groups（P 〉0.05）. Conclusion： The uremic clearance granule can effectually improve the renal function and curative effect of patients with chronic renal insufficiency.
关键词
尿毒清颗粒
慢性肾功能不全
疗效
Uremic clearance granule
Chronic renal insufficiency
Renal function
Curative effect
