摘要
目的探讨C反应蛋白(CRP)及慢阻肺患者自我评估测试(CAT)问卷在慢性阻塞性肺疾病(COPD)合并肺动脉高压(PH)患者病情评估中的意义。方法选择COPD急性加重期合并PH住院患者50例作为治疗组,检测患者的CRP、肺动脉收缩压(PASP)及CAT评分;给予患者正规治疗,在患者临床症状缓解时、缓解后1个月及3个月分别进行CRP、PASP、CAT评分指标的测定。选择同期正常健康体检者50例作为对照组,检测CRP;观察CRP、PASP的变化及相关性分析。结果 COPD组急性期CRP明显高于缓解期(P<0.05),缓解期CRP变化无明显差异(P>0.05),各时期CRP均明显高于对照组(P<0.05);COPD组急性期CAT评分明显高于缓解期(P<0.05),缓解期CAT评分变化和对照组无明显差异(P>0.05);COPD组CRP、CAT评分与PASP呈正相关(P<0.05)。结论 CRP及CAT问卷可以较好地反应COPD的病情发展和严重程度。
Objective To assess the value of C-reactive protein（CRP） and chronic obstructive pulmonary disease（COPD） patients self assessment test score（CAT） questionnaire in CRP with concurrent pulmonary hypertension. Methods To select 50 hospitalized patients of acute exacerbation chronic obstructive pulmonary disease（AECOPD） with pulmonary hypertension as the treatment group, and 50 normal healthy as the control group at the same time detect the CRP, PASP and CAT score of the treatment group and the control group,give conventional treatment to AECOPD patients, check the indicators above at the time of clinical remission,one month and three months after clinical symptoms remission, analyze the relativity of CRP and PASP.Results Acute CRP was obvious higher than remission in COPD group（P〈0.05）, the difference of CRP in the different remission time was not significant（P〈0.05）, all the CRP of COPD group is obvious higher than control group（P〈0.05）; acute CAT score was obvious higher than remission（P〈0.05）, the difference ofCAT score in the different remission time was not significant（P〈0.05）; the CRP and CAT score has positive proportion with PASP in COPD group（P〈0.05）. Conclusion The CRP and CAT questionnaire can better reflect the development and severity of COPD.
出处
《兰州大学学报（医学版）》
CAS
2017年第1期51-55,共5页
Journal of Lanzhou University（Medical Sciences）
关键词
C反应蛋白
慢性阻塞性肺疾病
肺动脉高压
慢阻肺患者自我评估测试
急性加重期
缓解期
C-reactive protein
chronic obstructive pulmonary disease
pulmonary arterial hypertension
chronic obstructive pulmonary disease patients self assessment test score
acute period
remission period
