摘要
目的评估C反应蛋白与其他变量在合并肺部感染的尘肺患者中的预测价值。方法尘肺患者285例，按照是否合并肺部感染分为两组：无肺部感染患者188例为A组。合并肺部感染的患者97例为B组。结果B纽患者年龄明显高于A组（P=0．008）；B组患者吸烟者的比例明显高于A组（P=0．000）；B组患者白细胞计数、中性粒细胞比例、CRP、接尘年限显著高于A组（P=0．000）；B组患者HDL．C水平明显高于A组，（P=0．006）；B组患者TcellCD4水平低于A纽，（P=0．002）。B组男性患者比例明显小于A组，（P=0．020）。B组患者患高血压比例小于A组（P=0．020）。B组患者尿酸水平低于A组（P=0．000）。结论经多变量logistic回归分析，CRP升高是尘肺患者合并肺部感染的独立预测因子。
Objective To evaluate the predictive value of c-reactive protein and other index in patients with pneumoconiosis complicated with pulmonary infection. Methods 285 cases of pneumoconiosis were divided into two groups according to whether complicated with pulmonary infection： Group A includes 188 cases without pulmonary infection, group B includes 97 cases with pulmonary infection. Results Group B patients＇ age was significantly higher than group A （P=0.008） ; group B patients＇ proportion of smokers, white blood cell count, neutrophils ratio, CRP, dust length of service were significantly higher than group A （ P=0.000 ） ; group B patients＇ HDL-C level was significantly higher in group A （ P=0.006 ） ; group B patients＇ T cell CD4 level lower than that of group A, （ P=0.002 ） .The proportion of men with group B was obviously less than group A （ P=0.020 ） ; the proportion of patients with hypertension in group B was less than that in group A （ P=0.007 ） ; the level of uric acid in group B was lower than that in group A （ P=0.000 ） . Conclusion After multivariate analysis, CRP elevation is an independent predictor of pneumoconiosis patients with pulmonary infection.
出处
《浙江临床医学》
2017年第3期460-462,共3页
Zhejiang Clinical Medical Journal
基金
江苏省苏州市科技计划项目（SS201542）
关键词
尘肺
肺部感染
CRP
接尘年限
Pneumoconiosis complicated Pulmonary infection C-reactive protein Dust length of service
